hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04534
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CLEC4A | C-type lectin domain family 4 member A (C-type lectin DDB27) (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor) (CD antigen CD367) | UniProt NCBI |
| RNASE7 | Ribonuclease 7 (RNase 7) (EC 3.1.27.-) (Skin-derived antimicrobial protein 2) (SAP-2) | UniProt NCBI |
| G3BP1 | Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1) | UniProt NCBI |
| ADD3 | Gamma-adducin (Adducin-like protein 70) | UniProt NCBI |
| ADD2 | Beta-adducin (Erythrocyte adducin subunit beta) | UniProt NCBI |
| ADD1 | Alpha-adducin (Erythrocyte adducin subunit alpha) | UniProt NCBI |
| FAM122B | Protein FAM122B | UniProt NCBI |
| DPPA4 | Developmental pluripotency-associated protein 4 | UniProt NCBI |
| ANKRD29 | Ankyrin repeat domain-containing protein 29 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5223345 | 4.02039297847e-05 | 0.333333333333 | ADD1 ADD3 ADD2 | Miscellaneous transport and binding events |
| GO:0051016 | 0.00735659813211 | 0.333333333333 | ADD1 ADD3 ADD2 | barbed-end actin filament capping |
| GO:0051693 | 0.00865220447533 | 0.333333333333 | ADD1 ADD3 ADD2 | actin filament capping |
| GO:0030507 | 0.010091186376 | 0.333333333333 | ADD1 ADD3 ADD2 | spectrin binding |
| GO:0030835 | 0.0116809984418 | 0.333333333333 | ADD1 ADD3 ADD2 | negative regulation of actin filament depolymerization |
| GO:0030834 | 0.03072093226 | 0.333333333333 | ADD1 ADD3 ADD2 | regulation of actin filament depolymerization |
| GO:0030837 | 0.045224564378 | 0.333333333333 | ADD1 ADD3 ADD2 | negative regulation of actin filament polymerization |
| GO:0030042 | 0.0494494038063 | 0.333333333333 | ADD1 ADD3 ADD2 | actin filament depolymerization |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ANKRD29 | ADD3 | 0.998 | 0.941 | bioplex (ANKRD29) bioplex_WMM |
| ADD2 | ANKRD29 | 0.677 | 0.706 | bioplex (ANKRD29) bioplex_WMM |
| ADD2 | ADD1 | 0.587 | 0.662 | bioplex (ADD2) bioplex_WMM gupta_WMM |
| ADD2 | DPPA4 | 0.428 | 0.576 | bioplex (DPPA4) bioplex_WMM |
| FAM122B | ANKRD29 | 0.225 | 0.465 | bioplex (ANKRD29) bioplex_WMM |
| ADD1 | ANKRD29 | 0.165 | 0.421 | bioplex (ANKRD29) bioplex_WMM |
| RNASE7 | DPPA4 | 0.044 | 0.279 | bioplex (DPPA4) bioplex_WMM |
| G3BP1 | ADD3 | 0.044 | 0.279 | youn (G3BP1) bioplex_WMM youn_WMM gupta_WMM fraction |
| CLEC4A | G3BP1 | 0.033 | 0.249 | fraction |
| ADD1 | ADD3 | 0.026 | 0.22 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ADD2 | ADD3 | 0.021 | 0.19 | bioplex (ADD2) bioplex_WMM gupta_WMM |
| ADD1 | DPPA4 | 0.013 | 0.145 | bioplex (DPPA4) bioplex_WMM |
| FAM122B | ADD2 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| FAM122B | ADD3 | 0.007 | 0.009 | bioplex_WMM gupta_WMM WMM_only |
| ADD2 | RNASE7 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| G3BP1 | ANKRD29 | 0.007 | 0.002 | bioplex (ANKRD29) |
| FAM122B | ADD1 | 0.007 | 0.001 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| FAM122B | G3BP1 | 0.007 | 0.001 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ADD1 | RNASE7 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| ADD2 | G3BP1 | 0.007 | 0.005 | bioplex (ADD2) gupta_WMM |
| G3BP1 | RNASE7 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| G3BP1 | DPPA4 | 0.007 | 0.004 | bioplex (DPPA4) |
| ADD1 | G3BP1 | 0.004 | 0.01 | youn (G3BP1) bioplex_WMM youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_04534 has an average edge precision of 0.225 which is ranked 5768 out of all 6965 complexes.
Related Complexes