hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04535
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SEPTIN2 | Septin-2 (Neural precursor cell expressed developmentally down-regulated protein 5) (NEDD-5) | UniProt NCBI |
| SEPTIN1 | Septin-1 (LARP) (Peanut-like protein 3) (Serologically defined breast cancer antigen NY-BR-24) | UniProt NCBI |
| SEPTIN6 | Septin-6 | UniProt NCBI |
| SEPTIN9 | Septin-9 (MLL septin-like fusion protein MSF-A) (MLL septin-like fusion protein) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1) | UniProt NCBI |
| SEPTIN7 | Septin-7 (CDC10 protein homolog) | UniProt NCBI |
| SEPTIN5 | Septin-5 (Cell division control-related protein 1) (CDCrel-1) (Peanut-like protein 1) | UniProt NCBI |
| SEPTIN8 | Septin-8 | UniProt NCBI |
| SEPTIN3 | Neuronal-specific septin-3 | UniProt NCBI |
| SEPTIN14 | Septin-14 | UniProt NCBI |
| SEPTIN10 | Septin-10 | UniProt NCBI |
| SEPTIN11 | Septin-11 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0032156 | 9.11394460692e-32 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | septin cytoskeleton |
| GO:0031105 | 9.11394460692e-32 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | septin complex |
| GO:0005940 | 9.11394460692e-32 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | septin ring |
| GO:0061640 | 1.34586516147e-20 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | cytoskeleton-dependent cytokinesis |
| GO:0044448 | 1.32553422751e-18 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | cell cortex part |
| GO:0000910 | 3.7270115695e-18 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | cytokinesis |
| GO:0005938 | 8.66838658622e-17 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | cell cortex |
| GO:0051301 | 1.43129393365e-16 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | cell division |
| GO:0003924 | 9.98218079985e-16 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | GTPase activity |
| CORUM:1345 | 5.12134059541e-15 | 0.454545454545 | SEPTIN9 SEPTIN2 SEPTIN11 SEPTIN7 SEPTIN8 | Septin complex |
| GO:0099568 | 8.56475300466e-15 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | cytoplasmic region |
| KEGG:05100 | 7.40263804235e-13 | 0.636363636364 | SEPTIN11 SEPTIN3 SEPTIN2 SEPTIN9 SEPTIN6 SEPTIN1 SEPTIN8 | Bacterial invasion of epithelial cells |
| GO:0017111 | 1.31939006759e-11 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | nucleoside-triphosphatase activity |
| GO:0016462 | 2.77868048605e-11 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | pyrophosphatase activity |
| GO:0016818 | 2.88038761591e-11 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| GO:0016817 | 2.88038761591e-11 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | hydrolase activity, acting on acid anhydrides |
| GO:0015630 | 2.75707947176e-09 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | microtubule cytoskeleton |
| GO:0022402 | 1.61852963497e-08 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | cell cycle process |
| GO:0044430 | 4.0206935217e-08 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | cytoskeletal part |
| GO:0007049 | 1.07746331475e-07 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | cell cycle |
| GO:0005856 | 4.31199221184e-07 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | cytoskeleton |
| GO:0016787 | 3.41379765754e-06 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | hydrolase activity |
| GO:0097227 | 0.000149729915117 | 0.272727272727 | SEPTIN2 SEPTIN7 SEPTIN6 | sperm annulus |
| GO:0071944 | 0.00438843859523 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | cell periphery |
| GO:0043232 | 0.00710075918147 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | intracellular non-membrane-bounded organelle |
| GO:0043228 | 0.00714487562581 | 1.0 | SEPTIN11 SEPTIN3 SEPTIN10 SEPTIN6 SEPTIN9 SEPTIN14 SEPTIN2 SEPTIN7 SEPTIN8 SEPTIN5 SEPTIN1 | non-membrane-bounded organelle |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SEPTIN7 | SEPTIN10 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN10,SEPTIN7) bioplex_WMM Guru hein (SEPTIN7) Malo fraction |
| SEPTIN2 | SEPTIN10 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN10,SEPTIN2) bioplex_WMM Guru hein (SEPTIN2) Malo fraction |
| SEPTIN7 | SEPTIN2 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN2,SEPTIN7) bioplex_WMM Guru boldt youn_WMM hein (SEPTIN2,SEPTIN7) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SEPTIN2 | SEPTIN9 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN2) bioplex_WMM boldt youn_WMM hein (SEPTIN2,SEPTIN9) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SEPTIN6 | SEPTIN2 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN2,SEPTIN6) bioplex_WMM Guru youn_WMM hein (SEPTIN2,SEPTIN6) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SEPTIN2 | SEPTIN11 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN2) bioplex_WMM Guru boldt youn_WMM hein (SEPTIN11,SEPTIN2) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SEPTIN8 | SEPTIN2 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN2) bioplex_WMM Guru youn_WMM hein (SEPTIN2) Malo gupta_WMM fraction |
| SEPTIN11 | SEPTIN9 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt youn_WMM hein (SEPTIN11,SEPTIN9) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SEPTIN6 | SEPTIN7 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN6,SEPTIN7) bioplex_WMM Guru youn_WMM hein (SEPTIN6,SEPTIN7) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SEPTIN7 | SEPTIN9 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN7) bioplex_WMM boldt youn_WMM hein (SEPTIN7,SEPTIN9) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SEPTIN7 | SEPTIN11 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN7) bioplex_WMM Guru boldt youn_WMM hein (SEPTIN11,SEPTIN7) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SEPTIN8 | SEPTIN7 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN7) bioplex_WMM Guru youn_WMM hein (SEPTIN7) Malo gupta_WMM fraction |
| SEPTIN6 | SEPTIN9 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN6) bioplex_WMM youn_WMM hein (SEPTIN6,SEPTIN9) gupta_WMM boldt_WMM treiber_WMM |
| SEPTIN6 | SEPTIN11 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN6) bioplex_WMM youn_WMM hein (SEPTIN11) gupta_WMM boldt_WMM |
| SEPTIN6 | SEPTIN5 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN6) bioplex_WMM Malo fraction |
| SEPTIN5 | SEPTIN1 | 1.0 | 0.949 | bioplex (SEPTIN1) bioplex_WMM |
| SEPTIN5 | SEPTIN7 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN7) bioplex_WMM Malo fraction |
| SEPTIN6 | SEPTIN10 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN10,SEPTIN6) bioplex_WMM hein (SEPTIN6) |
| SEPTIN14 | SEPTIN3 | 1.0 | 0.949 | bioplex (SEPTIN3) bioplex_WMM |
| SEPTIN5 | SEPTIN2 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN2) bioplex_WMM Malo fraction |
| SEPTIN8 | SEPTIN10 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN10) bioplex_WMM Malo fraction |
| SEPTIN5 | SEPTIN10 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN10) bioplex_WMM Malo fraction |
| SEPTIN5 | SEPTIN11 | 1.0 | 0.949 | hein_WMM bioplex_WMM Malo fraction |
| SEPTIN8 | SEPTIN5 | 0.999 | 0.949 | hein_WMM bioplex_WMM Malo fraction |
| SEPTIN7 | SEPTIN3 | 0.999 | 0.949 | bioplex (SEPTIN3,SEPTIN7) bioplex_WMM youn_WMM gupta_WMM |
| SEPTIN8 | SEPTIN3 | 0.999 | 0.949 | bioplex (SEPTIN3) bioplex_WMM youn_WMM gupta_WMM |
| SEPTIN6 | SEPTIN8 | 0.995 | 0.923 | hein_WMM bioplex (SEPTIN6) bioplex_WMM youn_WMM gupta_WMM |
| SEPTIN10 | SEPTIN9 | 0.994 | 0.921 | hein_WMM bioplex (SEPTIN10) bioplex_WMM hein (SEPTIN9) |
| SEPTIN7 | SEPTIN14 | 0.984 | 0.899 | bioplex (SEPTIN7) bioplex_WMM |
| SEPTIN2 | SEPTIN3 | 0.983 | 0.899 | bioplex (SEPTIN2,SEPTIN3) bioplex_WMM youn_WMM gupta_WMM |
| SEPTIN11 | SEPTIN10 | 0.98 | 0.896 | hein_WMM bioplex (SEPTIN10) bioplex_WMM hein (SEPTIN11) |
| SEPTIN11 | SEPTIN3 | 0.953 | 0.859 | bioplex (SEPTIN3) bioplex_WMM youn_WMM gupta_WMM |
| SEPTIN6 | SEPTIN3 | 0.944 | 0.856 | bioplex (SEPTIN3,SEPTIN6) bioplex_WMM youn_WMM gupta_WMM |
| SEPTIN6 | SEPTIN14 | 0.938 | 0.85 | bioplex (SEPTIN6) bioplex_WMM |
| SEPTIN10 | SEPTIN3 | 0.912 | 0.836 | bioplex (SEPTIN10,SEPTIN3) bioplex_WMM |
| SEPTIN8 | SEPTIN1 | 0.861 | 0.797 | bioplex (SEPTIN1) bioplex_WMM |
| SEPTIN10 | SEPTIN14 | 0.832 | 0.78 | bioplex (SEPTIN10) bioplex_WMM |
| SEPTIN8 | SEPTIN11 | 0.824 | 0.773 | hein_WMM bioplex_WMM youn_WMM hein (SEPTIN11) Malo gupta_WMM fraction |
| SEPTIN5 | SEPTIN3 | 0.806 | 0.767 | bioplex (SEPTIN3) bioplex_WMM |
| SEPTIN11 | SEPTIN1 | 0.79 | 0.758 | bioplex (SEPTIN1) bioplex_WMM |
| SEPTIN9 | SEPTIN1 | 0.716 | 0.73 | bioplex (SEPTIN1) bioplex_WMM treiber_WMM |
| SEPTIN6 | SEPTIN1 | 0.567 | 0.654 | bioplex (SEPTIN1) bioplex_WMM treiber_WMM |
| SEPTIN7 | SEPTIN1 | 0.548 | 0.642 | bioplex (SEPTIN1) bioplex_WMM |
| SEPTIN8 | SEPTIN9 | 0.51 | 0.63 | hein_WMM bioplex_WMM youn_WMM hein (SEPTIN9) gupta_WMM |
| SEPTIN1 | SEPTIN3 | 0.46 | 0.598 | bioplex (SEPTIN1) bioplex_WMM |
| SEPTIN2 | SEPTIN1 | 0.449 | 0.592 | bioplex (SEPTIN1) bioplex_WMM |
| SEPTIN9 | SEPTIN3 | 0.418 | 0.573 | bioplex (SEPTIN3) bioplex_WMM youn_WMM gupta_WMM |
| SEPTIN10 | SEPTIN1 | 0.367 | 0.542 | bioplex (SEPTIN1) bioplex_WMM |
| SEPTIN5 | SEPTIN14 | 0.016 | 0.156 | bioplex_WMM WMM_only |
| SEPTIN5 | SEPTIN9 | 0.015 | 0.148 | hein_WMM bioplex_WMM hein (SEPTIN9) |
| SEPTIN9 | SEPTIN14 | 0.015 | 0.149 | bioplex_WMM WMM_only |
| SEPTIN2 | SEPTIN14 | 0.015 | 0.149 | bioplex_WMM WMM_only |
| SEPTIN8 | SEPTIN14 | 0.015 | 0.138 | bioplex_WMM WMM_only |
| SEPTIN11 | SEPTIN14 | 0.015 | 0.14 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04535 has an average edge precision of 0.784 which is ranked 992 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SEPTIN2 | HuMAP2_03114 HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |
| SEPTIN1 | HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |
| SEPTIN6 | HuMAP2_00639 HuMAP2_03114 HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |
| SEPTIN9 | HuMAP2_03114 HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |
| SEPTIN7 | HuMAP2_03114 HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |
| SEPTIN5 | HuMAP2_01323 HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 |
| SEPTIN8 | HuMAP2_01323 HuMAP2_03114 HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 |
| SEPTIN3 | HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |
| SEPTIN14 | HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |
| SEPTIN10 | HuMAP2_03114 HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |
| SEPTIN11 | HuMAP2_03114 HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |