hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_04537
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IKZF1 | DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1) | UniProt NCBI |
| IKZF4 | Zinc finger protein Eos (Ikaros family zinc finger protein 4) | UniProt NCBI |
| IKZF2 | Zinc finger protein Helios (Ikaros family zinc finger protein 2) | UniProt NCBI |
| IKZF3 | Zinc finger protein Aiolos (Ikaros family zinc finger protein 3) | UniProt NCBI |
| KLHDC10 | Kelch domain-containing protein 10 | UniProt NCBI |
| IKZF5 | Zinc finger protein Pegasus (Ikaros family zinc finger protein 5) | UniProt NCBI |
| ZNF225 | Zinc finger protein 225 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| MIRNA:hsa-miR-1305 | 0.0145420418846 | 0.428571428571 | IKZF5 KLHDC10 ZNF225 | hsa-miR-1305 |
| MIRNA:hsa-miR-607 | 0.026140268682 | 0.428571428571 | IKZF5 KLHDC10 ZNF225 | hsa-miR-607 |
| CORUM:5441 | 0.0499886427319 | 0.142857142857 | IKZF4 | NRG1-IKZF4 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| IKZF3 | IKZF4 | 1.0 | 0.949 | bioplex (IKZF3) bioplex_WMM |
| IKZF1 | IKZF4 | 0.785 | 0.756 | bioplex (IKZF1) bioplex_WMM |
| IKZF1 | IKZF2 | 0.725 | 0.735 | bioplex (IKZF1) bioplex_WMM |
| IKZF1 | IKZF3 | 0.401 | 0.561 | bioplex (IKZF1) bioplex_WMM |
| IKZF2 | IKZF5 | 0.218 | 0.466 | bioplex (IKZF5) bioplex_WMM |
| IKZF5 | IKZF4 | 0.188 | 0.438 | bioplex (IKZF5) bioplex_WMM |
| IKZF1 | ZNF225 | 0.169 | 0.426 | bioplex (IKZF1) bioplex_WMM |
| IKZF5 | IKZF3 | 0.102 | 0.365 | bioplex (IKZF5) bioplex_WMM |
| IKZF1 | KLHDC10 | 0.062 | 0.344 | bioplex (IKZF1) bioplex_WMM |
| IKZF1 | IKZF5 | 0.013 | 0.149 | bioplex (IKZF1) bioplex_WMM |
| IKZF2 | IKZF3 | 0.01 | 0.128 | bioplex_WMM WMM_only |
| IKZF2 | IKZF4 | 0.01 | 0.128 | bioplex_WMM WMM_only |
| IKZF2 | ZNF225 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| ZNF225 | IKZF3 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| ZNF225 | IKZF4 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| ZNF225 | IKZF5 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| KLHDC10 | IKZF2 | 0.008 | 0.046 | bioplex_WMM WMM_only |
| KLHDC10 | IKZF3 | 0.008 | 0.028 | bioplex_WMM WMM_only |
| KLHDC10 | IKZF4 | 0.008 | 0.028 | bioplex_WMM WMM_only |
| KLHDC10 | IKZF5 | 0.008 | 0.028 | bioplex_WMM WMM_only |
| KLHDC10 | ZNF225 | 0.008 | 0.028 | bioplex_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_04537 has an average edge precision of 0.279 which is ranked 4902 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IKZF1 | HuMAP2_00201 HuMAP2_02782 HuMAP2_04537 HuMAP2_06687 |
| IKZF4 | HuMAP2_02782 HuMAP2_03693 HuMAP2_04537 |
| IKZF2 | HuMAP2_00201 HuMAP2_02782 HuMAP2_04537 HuMAP2_06687 |
| IKZF3 | HuMAP2_02782 HuMAP2_03693 HuMAP2_04537 |
| KLHDC10 | HuMAP2_00201 HuMAP2_00369 HuMAP2_00616 HuMAP2_02782 HuMAP2_04537 |
| IKZF5 | HuMAP2_01456 HuMAP2_04537 HuMAP2_05792 |
| ZNF225 | HuMAP2_00910 HuMAP2_04537 HuMAP2_04859 |