hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_04538
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HAUS6 | HAUS augmin-like complex subunit 6 | UniProt NCBI |
| HAUS7 | HAUS augmin-like complex subunit 7 (26S proteasome-associated UCH37-interacting protein 1) (UCHL5-interacting protein) (X-linked protein STS1769) | UniProt NCBI |
| HAUS1 | HAUS augmin-like complex subunit 1 (Coiled-coil domain-containing protein 5) (Enhancer of invasion-cluster) (HEI-C) | UniProt NCBI |
| HAUS2 | HAUS augmin-like complex subunit 2 (Centrosomal protein of 27 kDa) (Cep27) | UniProt NCBI |
| HAUS4 | HAUS augmin-like complex subunit 4 | UniProt NCBI |
| HAUS3 | HAUS augmin-like complex subunit 3 | UniProt NCBI |
| HAUS5 | HAUS augmin-like complex subunit 5 | UniProt NCBI |
| HAUS8 | HAUS augmin-like complex subunit 8 (HEC1/NDC80-interacting centrosome-associated protein 1) (Sarcoma antigen NY-SAR-48) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0070652 | 8.34096543393e-25 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | HAUS complex |
| CORUM:6435 | 1.14974030014e-23 | 0.875 | HAUS5 HAUS6 HAUS7 HAUS1 HAUS3 HAUS8 HAUS2 | HAUS augmin-like complex |
| REAC:R-HSA-380259 | 1.92917703261e-17 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | Loss of Nlp from mitotic centrosomes |
| REAC:R-HSA-380284 | 1.92917703261e-17 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | Loss of proteins required for interphase microtubule organization from the centrosome |
| REAC:R-HSA-8854518 | 2.79225676269e-17 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | AURKA Activation by TPX2 |
| REAC:R-HSA-380270 | 7.71651208669e-17 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | Recruitment of mitotic centrosome proteins and complexes |
| REAC:R-HSA-380287 | 7.71651208669e-17 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | Centrosome maturation |
| REAC:R-HSA-2565942 | 1.28945249109e-16 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | Regulation of PLK1 Activity at G2/M Transition |
| REAC:R-HSA-380320 | 2.29274569107e-16 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | Recruitment of NuMA to mitotic centrosomes |
| REAC:R-HSA-5620912 | 3.59522028125e-16 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | Anchoring of the basal body to the plasma membrane |
| GO:0051225 | 6.46554284882e-14 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | spindle assembly |
| GO:0097711 | 9.28475098739e-14 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | ciliary basal body-plasma membrane docking |
| REAC:R-HSA-69275 | 1.07303808361e-13 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | G2/M Transition |
| REAC:R-HSA-5617833 | 1.1199468523e-13 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | Cilium Assembly |
| REAC:R-HSA-68877 | 1.1199468523e-13 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | Mitotic Prometaphase |
| REAC:R-HSA-453274 | 1.1686401937e-13 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | Mitotic G2-G2/M phases |
| GO:0007098 | 2.93623360644e-13 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | centrosome cycle |
| GO:0031023 | 5.68793298287e-13 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | microtubule organizing center organization |
| GO:0005875 | 1.73797777074e-12 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | microtubule associated complex |
| REAC:R-HSA-1852241 | 2.43388104095e-12 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | Organelle biogenesis and maintenance |
| GO:0007051 | 3.1379373903e-12 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | spindle organization |
| GO:0140056 | 3.32117461017e-12 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | organelle localization by membrane tethering |
| GO:0022406 | 5.43982667702e-12 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | membrane docking |
| GO:0010389 | 1.62069782462e-11 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | regulation of G2/M transition of mitotic cell cycle |
| REAC:R-HSA-68886 | 2.77783317385e-11 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | M Phase |
| GO:1902749 | 3.29556534624e-11 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | regulation of cell cycle G2/M phase transition |
| GO:0000086 | 1.15551862675e-10 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | G2/M transition of mitotic cell cycle |
| GO:0044839 | 2.16492331472e-10 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | cell cycle G2/M phase transition |
| REAC:R-HSA-69278 | 3.49110510408e-10 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | Cell Cycle, Mitotic |
| REAC:R-HSA-1640170 | 1.49141200565e-09 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | Cell Cycle |
| GO:0060271 | 2.08254533136e-09 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | cilium assembly |
| GO:0044782 | 3.16504945902e-09 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | cilium organization |
| GO:1901990 | 4.10329516288e-09 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | regulation of mitotic cell cycle phase transition |
| GO:1901987 | 7.18694858314e-09 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | regulation of cell cycle phase transition |
| GO:0120031 | 3.09598196733e-08 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | plasma membrane bounded cell projection assembly |
| GO:0005813 | 3.50920889448e-08 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | centrosome |
| GO:0030031 | 3.63579948379e-08 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | cell projection assembly |
| GO:0000226 | 3.83317714996e-08 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | microtubule cytoskeleton organization |
| GO:0044772 | 4.5604866742e-08 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | mitotic cell cycle phase transition |
| GO:0051640 | 6.38514815718e-08 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | organelle localization |
| GO:0044770 | 7.63858337076e-08 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | cell cycle phase transition |
| GO:0007346 | 9.84491639349e-08 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | regulation of mitotic cell cycle |
| GO:0005815 | 3.22763833156e-07 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | microtubule organizing center |
| GO:0010564 | 3.54450540892e-07 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | regulation of cell cycle process |
| GO:0007017 | 4.66430679326e-07 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | microtubule-based process |
| GO:0070925 | 8.75742632059e-07 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | organelle assembly |
| GO:1903047 | 1.34335374186e-06 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | mitotic cell cycle process |
| GO:0000278 | 4.59221923352e-06 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | mitotic cell cycle |
| GO:0051726 | 8.6315104673e-06 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | regulation of cell cycle |
| GO:0015630 | 1.15260472251e-05 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | microtubule cytoskeleton |
| GO:0120036 | 2.17869797112e-05 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | plasma membrane bounded cell projection organization |
| GO:0030030 | 2.37663414302e-05 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | cell projection organization |
| GO:0007010 | 2.57005136845e-05 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | cytoskeleton organization |
| GO:0022402 | 4.16752355471e-05 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | cell cycle process |
| GO:0044430 | 8.0705247766e-05 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | cytoskeletal part |
| GO:0007049 | 0.000165146943803 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | cell cycle |
| GO:0005856 | 0.000452284610928 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | cytoskeleton |
| CORUM:0000000 | 0.00993810898821 | 0.875 | HAUS5 HAUS6 HAUS7 HAUS1 HAUS3 HAUS8 HAUS2 | CORUM root |
| GO:0022607 | 0.0157272559172 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | cellular component assembly |
| GO:0051641 | 0.0161157357033 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | cellular localization |
| GO:0044085 | 0.0296488714229 | 1.0 | HAUS6 HAUS5 HAUS7 HAUS8 HAUS1 HAUS3 HAUS4 HAUS2 | cellular component biogenesis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HAUS7 | HAUS2 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM hein (HAUS2) gupta_WMM |
| HAUS7 | HAUS4 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM hein (HAUS4) gupta_WMM |
| HAUS7 | HAUS1 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM hein (HAUS1) gupta_WMM |
| HAUS7 | HAUS3 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM gupta_WMM |
| HAUS7 | HAUS8 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM gupta_WMM |
| HAUS7 | HAUS5 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM gupta_WMM |
| HAUS7 | HAUS6 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM gupta_WMM |
| HAUS1 | HAUS4 | 0.997 | 0.934 | hein_WMM bioplex_WMM boldt youn_WMM hein (HAUS1,HAUS4) gupta_WMM boldt_WMM |
| HAUS2 | HAUS3 | 0.985 | 0.899 | hein_WMM bioplex_WMM youn_WMM hein (HAUS2) gupta_WMM |
| HAUS2 | HAUS8 | 0.978 | 0.894 | hein_WMM bioplex_WMM youn_WMM hein (HAUS2) gupta_WMM |
| HAUS4 | HAUS2 | 0.963 | 0.871 | hein_WMM bioplex_WMM youn_WMM hein (HAUS2,HAUS4) gupta_WMM |
| HAUS2 | HAUS5 | 0.944 | 0.856 | hein_WMM bioplex_WMM youn_WMM hein (HAUS2) gupta_WMM |
| HAUS1 | HAUS2 | 0.905 | 0.828 | hein_WMM bioplex_WMM youn_WMM hein (HAUS1,HAUS2) gupta_WMM |
| HAUS4 | HAUS3 | 0.851 | 0.791 | hein_WMM bioplex_WMM youn_WMM hein (HAUS4) gupta_WMM |
| HAUS4 | HAUS5 | 0.797 | 0.763 | hein_WMM bioplex_WMM youn_WMM hein (HAUS4) gupta_WMM |
| HAUS1 | HAUS3 | 0.756 | 0.747 | hein_WMM bioplex_WMM youn_WMM hein (HAUS1) gupta_WMM |
| HAUS4 | HAUS8 | 0.681 | 0.708 | hein_WMM bioplex_WMM youn_WMM hein (HAUS4) gupta_WMM |
| HAUS2 | HAUS6 | 0.632 | 0.681 | hein_WMM bioplex_WMM youn_WMM hein (HAUS2) gupta_WMM |
| HAUS6 | HAUS8 | 0.383 | 0.55 | hein_WMM bioplex (HAUS8) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| HAUS4 | HAUS6 | 0.33 | 0.52 | hein_WMM bioplex_WMM youn_WMM hein (HAUS4) gupta_WMM |
| HAUS1 | HAUS5 | 0.312 | 0.505 | hein_WMM bioplex_WMM youn_WMM hein (HAUS1) gupta_WMM |
| HAUS1 | HAUS6 | 0.161 | 0.418 | hein_WMM bioplex_WMM youn_WMM hein (HAUS1) gupta_WMM |
| HAUS1 | HAUS8 | 0.155 | 0.416 | hein_WMM bioplex_WMM youn_WMM hein (HAUS1) gupta_WMM |
| HAUS3 | HAUS8 | 0.022 | 0.205 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| HAUS5 | HAUS8 | 0.021 | 0.187 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| HAUS3 | HAUS5 | 0.018 | 0.178 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| HAUS6 | HAUS3 | 0.016 | 0.157 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| HAUS6 | HAUS5 | 0.016 | 0.154 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_04538 has an average edge precision of 0.675 which is ranked 1479 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HAUS6 | HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS7 | HuMAP2_00474 HuMAP2_03612 HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS1 | HuMAP2_00474 HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS2 | HuMAP2_00474 HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS4 | HuMAP2_00474 HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS3 | HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS5 | HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS8 | HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |