hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04544
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SMARCA5 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H) | UniProt NCBI |
| RBBP4 | Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) | UniProt NCBI |
| NASP | Nuclear autoantigenic sperm protein (NASP) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1150 | 7.04603414803e-05 | 0.666666666667 | RBBP4 NASP | Histone H3.3 complex |
| CORUM:1149 | 9.39429153233e-05 | 0.666666666667 | RBBP4 NASP | Histone H3.1 complex |
| CORUM:282 | 0.000402468266231 | 0.666666666667 | RBBP4 SMARCA5 | SNF2h-cohesin-NuRD complex |
| GO:0034080 | 0.00120280122085 | 1.0 | RBBP4 NASP SMARCA5 | CENP-A containing nucleosome assembly |
| GO:0061641 | 0.00120280122085 | 1.0 | RBBP4 NASP SMARCA5 | CENP-A containing chromatin organization |
| CORUM:1257 | 0.00126709356127 | 0.666666666667 | RBBP4 SMARCA5 | ALL-1 supercomplex |
| GO:0031055 | 0.00137862598403 | 1.0 | RBBP4 NASP SMARCA5 | chromatin remodeling at centromere |
| GO:0006336 | 0.00225266395968 | 1.0 | RBBP4 NASP SMARCA5 | DNA replication-independent nucleosome assembly |
| GO:0034508 | 0.00225266395968 | 1.0 | RBBP4 NASP SMARCA5 | centromere complex assembly |
| GO:0034724 | 0.00238262534197 | 1.0 | RBBP4 NASP SMARCA5 | DNA replication-independent nucleosome organization |
| GO:0043486 | 0.00265735153444 | 1.0 | RBBP4 NASP SMARCA5 | histone exchange |
| GO:0043044 | 0.0089701507538 | 1.0 | RBBP4 NASP SMARCA5 | ATP-dependent chromatin remodeling |
| REAC:R-HSA-774815 | 0.0170598073203 | 0.666666666667 | RBBP4 SMARCA5 | Nucleosome assembly |
| REAC:R-HSA-606279 | 0.0170598073203 | 0.666666666667 | RBBP4 SMARCA5 | Deposition of new CENPA-containing nucleosomes at the centromere |
| GO:0006334 | 0.0185411572066 | 1.0 | RBBP4 NASP SMARCA5 | nucleosome assembly |
| MIRNA:hsa-miR-8070 | 0.0196579207039 | 0.666666666667 | RBBP4 SMARCA5 | hsa-miR-8070 |
| GO:0016589 | 0.020283420769 | 0.666666666667 | RBBP4 SMARCA5 | NURF complex |
| REAC:R-HSA-5250913 | 0.0356968006044 | 0.666666666667 | RBBP4 SMARCA5 | Positive epigenetic regulation of rRNA expression |
| GO:0031497 | 0.0380729634404 | 1.0 | RBBP4 NASP SMARCA5 | chromatin assembly |
| REAC:R-HSA-73886 | 0.0385024292001 | 0.666666666667 | RBBP4 SMARCA5 | Chromosome Maintenance |
| CORUM:236 | 0.0499776345577 | 0.333333333333 | SMARCA5 | WICH complex |
| CORUM:921 | 0.0499776345577 | 0.333333333333 | SMARCA5 | Remodeling and spacing factor (RSF) complex |
| CORUM:925 | 0.0499776345577 | 0.333333333333 | SMARCA5 | SNF2H-BAZ1A complex |
| CORUM:5694 | 0.0499776345577 | 0.333333333333 | SMARCA5 | Nucleolar remodeling complex (NoRC complex) |
| CORUM:1458 | 0.0499776345577 | 0.333333333333 | SMARCA5 | SNF2h-HDAC12 complex |
| CORUM:94 | 0.0499776345577 | 0.333333333333 | SMARCA5 | SNF2H-BAZ1A complex |
| CORUM:7387 | 0.0499776345577 | 0.333333333333 | SMARCA5 | RSF complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RBBP4 | NASP | 1.0 | 0.949 | hein_WMM bioplex (NASP) bioplex_WMM boldt youn_WMM hein (NASP) gupta_WMM fraction boldt_WMM treiber_WMM |
| RBBP4 | SMARCA5 | 0.987 | 0.902 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction |
| SMARCA5 | NASP | 0.0 | 0.007 | youn_WMM gupta_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_04544 has an average edge precision of 0.619 which is ranked 1840 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SMARCA5 | HuMAP2_02937 HuMAP2_04544 HuMAP2_06754 |
| RBBP4 | HuMAP2_01771 HuMAP2_02289 HuMAP2_02937 HuMAP2_03645 HuMAP2_04544 HuMAP2_06754 |
| NASP | HuMAP2_04544 |