hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_04549
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SPTAN1 | Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit) | UniProt NCBI |
| ACTB | Actin, cytoplasmic 1 (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed] | UniProt NCBI |
| ACTBL2 | Beta-actin-like protein 2 (Kappa-actin) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5606 | 2.01342304124e-05 | 0.666666666667 | SPTAN1 ACTB | Emerin-actin-NMI-(alphaII)spectrin complex |
| CORUM:5608 | 5.03310689057e-05 | 0.666666666667 | SPTAN1 ACTB | Emerin architectural complex |
| CORUM:5604 | 9.39429153233e-05 | 0.666666666667 | SPTAN1 ACTB | Emerin complex 1 |
| CORUM:5614 | 0.000637127241024 | 0.666666666667 | SPTAN1 ACTB | Emerin complex 32 |
| WP:WP314 | 0.000824391260345 | 0.666666666667 | SPTAN1 ACTB | Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation |
| REAC:R-HSA-445095 | 0.00271504560844 | 0.666666666667 | SPTAN1 ACTB | Interaction between L1 and Ankyrins |
| KEGG:04210 | 0.00345163215546 | 0.666666666667 | SPTAN1 ACTB | Apoptosis |
| GO:0098973 | 0.00811409485621 | 0.666666666667 | ACTBL2 ACTB | structural constituent of postsynaptic actin cytoskeleton |
| GO:0005200 | 0.0106693663112 | 1.0 | SPTAN1 ACTB ACTBL2 | structural constituent of cytoskeleton |
| GO:0098918 | 0.0135228859698 | 0.666666666667 | ACTBL2 ACTB | structural constituent of synapse |
| REAC:R-HSA-1500931 | 0.0350118981581 | 0.666666666667 | SPTAN1 ACTB | Cell-Cell communication |
| REAC:R-HSA-373760 | 0.0406759452204 | 0.666666666667 | SPTAN1 ACTB | L1CAM interactions |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SPTAN1 | ACTB | 0.961 | 0.869 | hein_WMM bioplex_WMM hein (ACTB) gupta_WMM fraction boldt_WMM |
| ACTBL2 | ACTB | 0.786 | 0.757 | hein_WMM bioplex (ACTBL2) bioplex_WMM boldt hein (ACTB) gupta_WMM fraction boldt_WMM |
| SPTAN1 | ACTBL2 | 0.004 | 0.009 | hein_WMM bioplex (ACTBL2) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
Images
Click to enlarge
Complex HuMAP2_04549 has an average edge precision of 0.545 which is ranked 2232 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SPTAN1 | HuMAP2_00229 HuMAP2_01215 HuMAP2_01488 HuMAP2_01543 HuMAP2_04549 |
| ACTB | HuMAP2_04549 HuMAP2_05657 HuMAP2_06725 |
| ACTBL2 | HuMAP2_03285 HuMAP2_04261 HuMAP2_04549 HuMAP2_06725 |