hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04558
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| STXBP5L | Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2) | UniProt NCBI |
| VAMP3 | Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3) | UniProt NCBI |
| STXBP2 | Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B) | UniProt NCBI |
| STX19 | Syntaxin-19 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04130 | 0.000991147720711 | 0.5 | VAMP3 STX19 | SNARE interactions in vesicular transport |
| GO:0031201 | 0.00550256096709 | 0.75 | STX19 STXBP5L VAMP3 | SNARE complex |
| GO:0000149 | 0.0410761885593 | 0.75 | STXBP5L STXBP2 STX19 | SNARE binding |
| MIRNA:hsa-miR-365b-3p | 0.0470445231599 | 0.5 | VAMP3 STXBP2 | hsa-miR-365b-3p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| STXBP2 | STX19 | 0.929 | 0.845 | bioplex (STX19) bioplex_WMM |
| STXBP5L | STX19 | 0.659 | 0.696 | bioplex (STX19) bioplex_WMM |
| VAMP3 | STX19 | 0.096 | 0.359 | bioplex (STX19) bioplex_WMM |
| STXBP2 | STXBP5L | 0.008 | 0.089 | bioplex_WMM WMM_only |
| VAMP3 | STXBP5L | 0.008 | 0.083 | bioplex_WMM WMM_only |
| VAMP3 | STXBP2 | 0.008 | 0.066 | bioplex_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_04558 has an average edge precision of 0.356 which is ranked 3818 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| STXBP5L | HuMAP2_01360 HuMAP2_02482 HuMAP2_02881 HuMAP2_04558 |
| VAMP3 | HuMAP2_00003 HuMAP2_00644 HuMAP2_02881 HuMAP2_04558 |
| STXBP2 | HuMAP2_00351 HuMAP2_02482 HuMAP2_02881 HuMAP2_04558 HuMAP2_05336 HuMAP2_05409 HuMAP2_05553 HuMAP2_05838 |
| STX19 | HuMAP2_01360 HuMAP2_02482 HuMAP2_02881 HuMAP2_04558 HuMAP2_05409 |