hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04560
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IGF2BP1 | Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1) | UniProt NCBI |
| IGF2BP3 | Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3) | UniProt NCBI |
| LARP1 | La-related protein 1 (La ribonucleoprotein domain family member 1) | UniProt NCBI |
| RRBP1 | Ribosome-binding protein 1 (180 kDa ribosome receptor homolog) (RRp) (ES/130-related protein) (Ribosome receptor protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-428359 | 3.01639213985e-05 | 0.5 | IGF2BP1 IGF2BP3 | Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA |
| GO:0048027 | 0.00064271072446 | 0.75 | IGF2BP1 LARP1 IGF2BP3 | mRNA 5'-UTR binding |
| MIRNA:hsa-miR-5195-5p | 0.0113006207749 | 0.5 | IGF2BP1 IGF2BP3 | hsa-miR-5195-5p |
| MIRNA:hsa-let-7b-5p | 0.0124981666289 | 1.0 | IGF2BP1 LARP1 RRBP1 IGF2BP3 | hsa-let-7b-5p |
| MIRNA:hsa-miR-4278 | 0.0163424025137 | 0.5 | IGF2BP3 LARP1 | hsa-miR-4278 |
| MIRNA:hsa-let-7f-5p | 0.0179604053881 | 0.75 | IGF2BP1 LARP1 IGF2BP3 | hsa-let-7f-5p |
| GO:0003730 | 0.023464682987 | 0.75 | IGF2BP1 LARP1 IGF2BP3 | mRNA 3'-UTR binding |
| WP:WP3302 | 0.0333519728792 | 0.25 | IGF2BP1 | eIF5A regulation in response to inhibition of the nuclear export system |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| IGF2BP1 | IGF2BP3 | 0.993 | 0.918 | hein_WMM bioplex_WMM Malo gupta_WMM fraction treiber_WMM |
| LARP1 | IGF2BP1 | 0.735 | 0.738 | hein_WMM youn (IGF2BP1) bioplex_WMM gupta_WMM fraction treiber_WMM |
| LARP1 | IGF2BP3 | 0.201 | 0.45 | hein_WMM bioplex_WMM gupta_WMM fraction treiber_WMM |
| LARP1 | RRBP1 | 0.153 | 0.412 | hein_WMM bioplex_WMM hein (RRBP1) gupta_WMM fraction treiber_WMM |
| RRBP1 | IGF2BP3 | 0.023 | 0.209 | hein_WMM bioplex_WMM hein (RRBP1) gupta_WMM fraction treiber_WMM |
| IGF2BP1 | RRBP1 | 0.003 | 0.012 | bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_04560 has an average edge precision of 0.457 which is ranked 2825 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IGF2BP1 | HuMAP2_00556 HuMAP2_03425 HuMAP2_04560 HuMAP2_04632 HuMAP2_06751 |
| IGF2BP3 | HuMAP2_03425 HuMAP2_04560 HuMAP2_06751 |
| LARP1 | HuMAP2_00428 HuMAP2_04560 HuMAP2_04632 HuMAP2_05552 HuMAP2_05734 |
| RRBP1 | HuMAP2_04560 |