hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04563
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| COPS6 | COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6) (JAB1-containing signalosome subunit 6) (MOV34 homolog) (Vpr-interacting protein) (hVIP) | UniProt NCBI |
| COPS2 | COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2174 | 4.69258569465e-05 | 1.0 | COPS6 COPS2 | COP9 signalosome complex |
| CORUM:2179 | 6.03332446455e-05 | 1.0 | COPS6 COPS2 | CNS-P53 complex |
| CORUM:726 | 0.000110610948517 | 1.0 | COPS6 COPS2 | DDB2 complex |
| CORUM:727 | 0.000110610948517 | 1.0 | COPS6 COPS2 | CSA complex |
| CORUM:728 | 0.000130722030065 | 1.0 | COPS6 COPS2 | CSA-POLIIa complex |
| REAC:R-HSA-5696394 | 0.00117817419405 | 1.0 | COPS6 COPS2 | DNA Damage Recognition in GG-NER |
| REAC:R-HSA-6781823 | 0.00230942253115 | 1.0 | COPS6 COPS2 | Formation of TC-NER Pre-Incision Complex |
| REAC:R-HSA-6781827 | 0.00503279815751 | 1.0 | COPS6 COPS2 | Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
| REAC:R-HSA-5696399 | 0.00584226918984 | 1.0 | COPS6 COPS2 | Global Genome Nucleotide Excision Repair (GG-NER) |
| REAC:R-HSA-8856825 | 0.00656291627866 | 1.0 | COPS6 COPS2 | Cargo recognition for clathrin-mediated endocytosis |
| WP:WP4352 | 0.0083331540652 | 1.0 | COPS6 COPS2 | Ciliary landscape |
| REAC:R-HSA-5696398 | 0.0100471611569 | 1.0 | COPS6 COPS2 | Nucleotide Excision Repair |
| REAC:R-HSA-8856828 | 0.0138364241054 | 1.0 | COPS6 COPS2 | Clathrin-mediated endocytosis |
| GO:0000338 | 0.020287053512 | 1.0 | COPS6 COPS2 | protein deneddylation |
| REAC:R-HSA-8951664 | 0.0411120784555 | 1.0 | COPS6 COPS2 | Neddylation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| COPS6 | COPS2 | 1.0 | 0.949 | hein_WMM bioplex (COPS2,COPS6) bioplex_WMM Guru boldt youn_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_04563 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| COPS6 | HuMAP2_01049 HuMAP2_04563 HuMAP2_05105 HuMAP2_06808 |
| COPS2 | HuMAP2_01049 HuMAP2_04563 HuMAP2_05105 HuMAP2_06808 |