hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04573
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| UBQLN2 | Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2) | UniProt NCBI |
| TXNDC17 | Thioredoxin domain-containing protein 17 (14 kDa thioredoxin-related protein) (TRP14) (Protein 42-9-9) (Thioredoxin-like protein 5) | UniProt NCBI |
| IDH2 | Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6948 | 0.0249904952816 | 0.333333333333 | IDH2 | Isocitrate dehydrogenase [NADP], mitochondrial |
| WP:WP4519 | 0.0499785733994 | 0.333333333333 | IDH2 | Cerebral Organic Acidurias, including diseases |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TXNDC17 | IDH2 | 0.937 | 0.85 | bioplex_WMM fraction |
| IDH2 | UBQLN2 | 0.914 | 0.838 | bioplex_WMM boldt fraction boldt_WMM |
| TXNDC17 | UBQLN2 | 0.0 | 0.001 | bioplex_WMM fraction |
Images
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Complex HuMAP2_04573 has an average edge precision of 0.563 which is ranked 2117 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| UBQLN2 | HuMAP2_04319 HuMAP2_04573 HuMAP2_04761 |
| TXNDC17 | HuMAP2_00843 HuMAP2_02703 HuMAP2_03127 HuMAP2_03244 HuMAP2_04319 HuMAP2_04573 HuMAP2_05984 |
| IDH2 | HuMAP2_00843 HuMAP2_03723 HuMAP2_04319 HuMAP2_04573 HuMAP2_05984 HuMAP2_06767 |