hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04576
Confidence: Medium  
ProteinsGenename | Protein Name | Links |
---|---|---|
AKR1E2 | 1,5-anhydro-D-fructose reductase (AF reductase) (EC 1.1.1.263) (Aldo-keto reductase family 1 member C-like protein 2) (Aldo-keto reductase family 1 member E2) (LoopADR) (Testis aldo-keto reductase) (htAKR) (Testis-specific protein) (hTSP) | UniProt   NCBI |
RPE | Ribulose-phosphate 3-epimerase (EC 5.1.3.1) (Ribulose-5-phosphate-3-epimerase) | UniProt   NCBI |
PYGL | Glycogen phosphorylase, liver form (EC 2.4.1.1) | UniProt   NCBI |
PYGM | Glycogen phosphorylase, muscle form (EC 2.4.1.1) (Myophosphorylase) | UniProt   NCBI |
PYGB | Glycogen phosphorylase, brain form (EC 2.4.1.1) | UniProt   NCBI |
APOD | Apolipoprotein D (Apo-D) (ApoD) | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  GO:0008184 | 1.81637152046e-06 | 0.5 | PYGB PYGL PYGM | glycogen phosphorylase activity |
  REAC:R-HSA-70221 | 2.16413418261e-06 | 0.5 | PYGB PYGL PYGM | Glycogen breakdown (glycogenolysis) |
  KEGG:00500 | 7.52786831789e-06 | 0.5 | PYGB PYGL PYGM | Starch and sucrose metabolism |
  WP:WP500 | 1.25967140138e-05 | 0.5 | PYGB PYGL PYGM | Glycogen Synthesis and Degradation |
  REAC:R-HSA-8982491 | 1.54300761667e-05 | 0.5 | PYGB PYGL PYGM | Glycogen metabolism |
  GO:0004645 | 1.81582264982e-05 | 0.5 | PYGB PYGL PYGM | phosphorylase activity |
  GO:0055114 | 3.83256380661e-05 | 1.0 | PYGB PYGM AKR1E2 APOD RPE PYGL | oxidation-reduction process |
  REAC:R-HSA-71387 | 0.000223864296418 | 0.666666666667 | PYGB RPE PYGL PYGM | Metabolism of carbohydrates |
  KEGG:04922 | 0.000236939175691 | 0.5 | PYGB PYGL PYGM | Glucagon signaling pathway |
  KEGG:04931 | 0.000284472522745 | 0.5 | PYGB PYGL PYGM | Insulin resistance |
  KEGG:04910 | 0.000524612840052 | 0.5 | PYGB PYGL PYGM | Insulin signaling pathway |
  KEGG:04217 | 0.000943477416632 | 0.5 | PYGB PYGL PYGM | Necroptosis |
  GO:0005980 | 0.00101517134288 | 0.5 | PYGB PYGL PYGM | glycogen catabolic process |
  GO:0009251 | 0.00123252169378 | 0.5 | PYGB PYGL PYGM | glucan catabolic process |
  GO:0044247 | 0.00123252169378 | 0.5 | PYGB PYGL PYGM | cellular polysaccharide catabolic process |
  GO:0000272 | 0.00123252169378 | 0.5 | PYGB PYGL PYGM | polysaccharide catabolic process |
  GO:0030170 | 0.00175581235783 | 0.5 | PYGB PYGL PYGM | pyridoxal phosphate binding |
  GO:0070279 | 0.00175581235783 | 0.5 | PYGB PYGL PYGM | vitamin B6 binding |
  GO:0005975 | 0.00317685314296 | 0.833333333333 | PYGB RPE APOD PYGL PYGM | carbohydrate metabolic process |
  GO:0016052 | 0.00811327342942 | 0.666666666667 | PYGB RPE PYGL PYGM | carbohydrate catabolic process |
  GO:0044275 | 0.00813009778332 | 0.5 | PYGB PYGL PYGM | cellular carbohydrate catabolic process |
  GO:0044262 | 0.0104487739309 | 0.666666666667 | PYGB RPE PYGL PYGM | cellular carbohydrate metabolic process |
  GO:0019842 | 0.0292571070793 | 0.5 | PYGB PYGL PYGM | vitamin binding |
  GO:0005977 | 0.0312028564126 | 0.5 | PYGB PYGL PYGM | glycogen metabolic process |
  KEGG:01100 | 0.0331288091988 | 0.666666666667 | PYGB RPE PYGL PYGM | Metabolic pathways |
  GO:0006073 | 0.0332327932613 | 0.5 | PYGB PYGL PYGM | cellular glucan metabolic process |
  GO:0044042 | 0.0332327932613 | 0.5 | PYGB PYGL PYGM | glucan metabolic process |
  GO:0006112 | 0.0447070305646 | 0.5 | PYGB PYGL PYGM | energy reserve metabolic process |
Edges
Protein 1 | Protein 2 | Score | Precision | Evidence |
---|---|---|---|---|
 RPE |  PYGL | 0.033 | 0.247           | bioplex (RPE)     fraction     |
 AKR1E2 |  RPE | 0.031 | 0.239           | fraction     |
 PYGB |  RPE | 0.026 | 0.215           | fraction     |
 RPE |  APOD | 0.025 | 0.211           | bioplex (RPE)     bioplex_WMM     |
 RPE |  PYGM | 0.022 | 0.206           | fraction     |
 PYGB |  PYGL | 0.01 | 0.126           | bioplex_WMM     youn_WMM     gupta_WMM     WMM_only     treiber_WMM     |
 PYGB |  PYGM | 0.007 | 0.007           | youn_WMM     WMM_only     |
 PYGL |  PYGM | 0.007 | 0.003           | bioplex_WMM     WMM_only     |
 PYGB |  APOD | 0.007 | 0.002           | bioplex_WMM     WMM_only     |
 PYGL |  APOD | 0.007 | 0.006           | WMM_only     boldt_WMM     |
 APOD |  PYGM | 0.006 | 0.003           | bioplex_WMM     WMM_only     boldt_WMM     |
Images
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Complex HuMAP2_04576 has an average edge precision of 0.115 which is ranked 6890 out of all 6965 complexes.
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