hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04579
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CAT | Catalase (EC 1.11.1.6) | UniProt NCBI |
| IDI1 | Isopentenyl-diphosphate Delta-isomerase 1 (EC 5.3.3.2) (Isopentenyl pyrophosphate isomerase 1) (IPP isomerase 1) (IPPI1) | UniProt NCBI |
| GOT2 | Aspartate aminotransferase, mitochondrial (mAspAT) (EC 2.6.1.1) (EC 2.6.1.7) (Fatty acid-binding protein) (FABP-1) (Glutamate oxaloacetate transaminase 2) (Kynurenine aminotransferase 4) (Kynurenine aminotransferase IV) (Kynurenine--oxoglutarate transaminase 4) (Kynurenine--oxoglutarate transaminase IV) (Plasma membrane-associated fatty acid-binding protein) (FABPpm) (Transaminase A) | UniProt NCBI |
| ACO2 | Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:01200 | 6.43452048828e-05 | 0.75 | ACO2 CAT GOT2 | Carbon metabolism |
| KEGG:01210 | 0.000272131870234 | 0.5 | ACO2 GOT2 | 2-Oxocarboxylic acid metabolism |
| KEGG:00630 | 0.000869408386689 | 0.5 | ACO2 CAT | Glyoxylate and dicarboxylate metabolism |
| WP:WP4290 | 0.00144137960059 | 0.5 | ACO2 GOT2 | Metabolic reprogramming in colon cancer |
| KEGG:01100 | 0.00203701694021 | 1.0 | IDI1 CAT ACO2 GOT2 | Metabolic pathways |
| KEGG:01230 | 0.00494838688052 | 0.5 | ACO2 GOT2 | Biosynthesis of amino acids |
| WP:WP3925 | 0.0063819591539 | 0.5 | ACO2 GOT2 | Amino Acid metabolism |
| KEGG:00400 | 0.0397753158041 | 0.25 | GOT2 | Phenylalanine, tyrosine and tryptophan biosynthesis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ACO2 | GOT2 | 0.981 | 0.896 | bioplex (GOT2) bioplex_WMM fraction treiber_WMM |
| ACO2 | IDI1 | 0.648 | 0.686 | bioplex (IDI1) bioplex_WMM fraction |
| CAT | ACO2 | 0.629 | 0.681 | bioplex_WMM fraction |
| GOT2 | IDI1 | 0.0 | 0.012 | bioplex (IDI1) bioplex_WMM fraction |
| CAT | IDI1 | 0.0 | 0.0 | bioplex_WMM fraction |
| CAT | GOT2 | 0.0 | 0.001 | bioplex (GOT2) bioplex_WMM fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_04579 has an average edge precision of 0.379 which is ranked 3530 out of all 6965 complexes.
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