hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04583
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NDUFC2 | NADH dehydrogenase [ubiquinone] 1 subunit C2 (Complex I-B14.5b) (CI-B14.5b) (Human lung cancer oncogene 1 protein) (HLC-1) (NADH-ubiquinone oxidoreductase subunit B14.5b) | UniProt NCBI |
| ECSIT | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Protein SITPEC) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4324 | 0.000513417075107 | 1.0 | ECSIT NDUFC2 | Mitochondrial complex I assembly model OXPHOS system |
| REAC:R-HSA-6799198 | 0.00222227451111 | 1.0 | ECSIT NDUFC2 | Complex I biogenesis |
| REAC:R-HSA-611105 | 0.00732546145404 | 1.0 | ECSIT NDUFC2 | Respiratory electron transport |
| REAC:R-HSA-163200 | 0.011178409494 | 1.0 | ECSIT NDUFC2 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| REAC:R-HSA-1428517 | 0.0226752444459 | 1.0 | ECSIT NDUFC2 | The citric acid (TCA) cycle and respiratory electron transport |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ECSIT | NDUFC2 | 0.194 | 0.446 | bioplex (ECSIT) bioplex_WMM |
Images
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Complex HuMAP2_04583 has an average edge precision of 0.446 which is ranked 2904 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NDUFC2 | HuMAP2_00306 HuMAP2_04089 HuMAP2_04583 HuMAP2_04892 |
| ECSIT | HuMAP2_00306 HuMAP2_02635 HuMAP2_04089 HuMAP2_04583 HuMAP2_04892 |