hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04590
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| APOOL | MICOS complex subunit MIC27 (Apolipoprotein O-like) (Protein FAM121A) | UniProt NCBI |
| CHCHD3 | MICOS complex subunit MIC19 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 3) | UniProt NCBI |
| AIFM1 | Apoptosis-inducing factor 1, mitochondrial (EC 1.1.1.-) (Programmed cell death protein 8) | UniProt NCBI |
| TOR1AIP1 | Torsin-1A-interacting protein 1 (Lamin-associated protein 1B) (LAP1B) | UniProt NCBI |
| CHCHD4 | Mitochondrial intermembrane space import and assembly protein 40 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6255 | 0.000100576175246 | 0.4 | CHCHD3 APOOL | MICOS complex |
| CORUM:6249 | 0.000301566439547 | 0.4 | CHCHD3 APOOL | MIB complex |
| REAC:R-HSA-8949613 | 0.00584945327803 | 0.4 | CHCHD3 APOOL | Cristae formation |
| REAC:R-HSA-1268020 | 0.0237053784759 | 0.4 | CHCHD4 CHCHD3 | Mitochondrial protein import |
| GO:0031967 | 0.0253087624128 | 1.0 | CHCHD4 APOOL CHCHD3 AIFM1 TOR1AIP1 | organelle envelope |
| GO:0031975 | 0.0253087624128 | 1.0 | CHCHD4 APOOL CHCHD3 AIFM1 TOR1AIP1 | envelope |
| CORUM:5843 | 0.0499494897235 | 0.2 | AIFM1 | AIF-CYPA-DNA complex |
| CORUM:7482 | 0.0499494897235 | 0.2 | TOR1AIP1 | LAP1-TOR1A complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CHCHD4 | AIFM1 | 0.726 | 0.736 | hein_WMM bioplex (AIFM1) bioplex_WMM boldt youn_WMM hein (AIFM1) boldt_WMM |
| CHCHD4 | TOR1AIP1 | 0.042 | 0.269 | hein_WMM bioplex (TOR1AIP1) bioplex_WMM hein (TOR1AIP1) |
| AIFM1 | TOR1AIP1 | 0.037 | 0.268 | hein_WMM bioplex (AIFM1,TOR1AIP1) bioplex_WMM youn_WMM hein (TOR1AIP1) |
| AIFM1 | APOOL | 0.028 | 0.232 | bioplex (AIFM1) bioplex_WMM youn_WMM |
| CHCHD3 | AIFM1 | 0.023 | 0.211 | hein_WMM bioplex (AIFM1) bioplex_WMM boldt youn_WMM hein (AIFM1) boldt_WMM |
| CHCHD3 | CHCHD4 | 0.006 | 0.001 | hein_WMM bioplex_WMM boldt boldt_WMM |
| CHCHD4 | APOOL | 0.006 | 0.008 | bioplex_WMM WMM_only |
| TOR1AIP1 | APOOL | 0.005 | 0.014 | bioplex_WMM WMM_only |
| CHCHD3 | APOOL | 0.004 | 0.012 | bioplex_WMM WMM_only |
| CHCHD3 | TOR1AIP1 | 0.003 | 0.016 | hein_WMM bioplex (TOR1AIP1) bioplex_WMM youn_WMM hein (TOR1AIP1) gupta_WMM |
Images
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Complex HuMAP2_04590 has an average edge precision of 0.177 which is ranked 6457 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| APOOL | HuMAP2_02740 HuMAP2_04590 |
| CHCHD3 | HuMAP2_01309 HuMAP2_03066 HuMAP2_04590 HuMAP2_04962 HuMAP2_06446 |
| AIFM1 | HuMAP2_02046 HuMAP2_02740 HuMAP2_02864 HuMAP2_04590 HuMAP2_05271 HuMAP2_06812 |
| TOR1AIP1 | HuMAP2_02046 HuMAP2_02740 HuMAP2_03597 HuMAP2_04590 HuMAP2_05271 |
| CHCHD4 | HuMAP2_02046 HuMAP2_02740 HuMAP2_02864 HuMAP2_03597 HuMAP2_04590 HuMAP2_05271 |