hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04603
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HIKESHI | Protein Hikeshi | UniProt NCBI |
| AKR1E2 | 1,5-anhydro-D-fructose reductase (AF reductase) (EC 1.1.1.263) (Aldo-keto reductase family 1 member C-like protein 2) (Aldo-keto reductase family 1 member E2) (LoopADR) (Testis aldo-keto reductase) (htAKR) (Testis-specific protein) (hTSP) | UniProt NCBI |
| MTHFD1 | C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Cleaved into: C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed] [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)] | UniProt NCBI |
| DNM1L | Dynamin-1-like protein (EC 3.6.5.5) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-like protein) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV) (Dynamin-related protein 1) | UniProt NCBI |
| SMAP1 | Stromal membrane-associated protein 1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0001972 | 0.0499382869304 | 0.4 | DNM1L MTHFD1 | Macrocytic anemia |
| CORUM:4200 | 0.0499494897235 | 0.2 | DNM1L | DNM1L-FIS1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MTHFD1 | AKR1E2 | 0.671 | 0.704 | fraction |
| MTHFD1 | DNM1L | 0.23 | 0.467 | bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| MTHFD1 | SMAP1 | 0.13 | 0.4 | youn_WMM fraction |
| HIKESHI | DNM1L | 0.072 | 0.354 | fraction |
| SMAP1 | DNM1L | 0.01 | 0.103 | youn_WMM fraction |
Images
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Complex HuMAP2_04603 has an average edge precision of 0.406 which is ranked 3261 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HIKESHI | HuMAP2_01649 HuMAP2_02386 HuMAP2_03705 HuMAP2_04603 |
| AKR1E2 | HuMAP2_00869 HuMAP2_02118 HuMAP2_04245 HuMAP2_04576 HuMAP2_04603 HuMAP2_04763 HuMAP2_06767 |
| MTHFD1 | HuMAP2_00843 HuMAP2_02118 HuMAP2_02671 HuMAP2_03723 HuMAP2_04603 HuMAP2_04763 HuMAP2_05984 HuMAP2_06767 |
| DNM1L | HuMAP2_02386 HuMAP2_04603 |
| SMAP1 | HuMAP2_02118 HuMAP2_04603 HuMAP2_05915 HuMAP2_06767 |