hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04615
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| POFUT2 | GDP-fucose protein O-fucosyltransferase 2 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 2) (O-FucT-2) | UniProt NCBI |
| CORO1C | Coronin-1C (Coronin-3) (hCRNN4) | UniProt NCBI |
| SSH2 | Protein phosphatase Slingshot homolog 2 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 2) (SSH-2L) (hSSH-2L) | UniProt NCBI |
| PPP1R9B | Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin) | UniProt NCBI |
| SYNPO | Synaptopodin | UniProt NCBI |
| CTTN | Src substrate cortactin (Amplaxin) (Oncogene EMS1) | UniProt NCBI |
| PLEKHG3 | Pleckstrin homology domain-containing family G member 3 (PH domain-containing family G member 3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0003779 | 0.00171877074275 | 0.714285714286 | CORO1C CTTN SYNPO PPP1R9B SSH2 | actin binding |
| GO:0030036 | 0.0406938796461 | 0.714285714286 | CORO1C CTTN SYNPO PPP1R9B SSH2 | actin cytoskeleton organization |
| CORUM:1130 | 0.0499886427319 | 0.142857142857 | CTTN | Hip1R-cortactin complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CTTN | CORO1C | 0.059 | 0.333 | hein_WMM bioplex_WMM boldt hein (CORO1C) gupta_WMM boldt_WMM treiber_WMM |
| SYNPO | CORO1C | 0.051 | 0.296 | hein_WMM hein (CORO1C) |
| CORO1C | SSH2 | 0.038 | 0.264 | hein_WMM bioplex_WMM hein (CORO1C) |
| CORO1C | PPP1R9B | 0.038 | 0.264 | hein_WMM bioplex_WMM hein (CORO1C) gupta_WMM |
| POFUT2 | CORO1C | 0.036 | 0.266 | bioplex_WMM gupta_WMM fraction |
| CORO1C | PLEKHG3 | 0.028 | 0.231 | hein_WMM bioplex_WMM hein (CORO1C) |
| SSH2 | PLEKHG3 | 0.01 | 0.103 | hein_WMM bioplex_WMM WMM_only |
| PPP1R9B | SSH2 | 0.008 | 0.023 | hein_WMM bioplex_WMM WMM_only |
| PPP1R9B | PLEKHG3 | 0.007 | 0.004 | hein_WMM WMM_only |
| POFUT2 | PPP1R9B | 0.007 | 0.005 | bioplex_WMM WMM_only |
| CTTN | POFUT2 | 0.007 | 0.004 | bioplex_WMM gupta_WMM WMM_only |
| POFUT2 | SSH2 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| CTTN | PPP1R9B | 0.006 | 0.007 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| SYNPO | PPP1R9B | 0.006 | 0.003 | hein_WMM WMM_only |
| SYNPO | SSH2 | 0.006 | 0.003 | hein_WMM WMM_only |
| SYNPO | PLEKHG3 | 0.006 | 0.011 | hein_WMM WMM_only |
| CTTN | SYNPO | 0.005 | 0.011 | hein_WMM WMM_only |
| CTTN | SSH2 | 0.005 | 0.008 | hein_WMM bioplex_WMM WMM_only |
| CTTN | PLEKHG3 | 0.005 | 0.01 | hein_WMM WMM_only |
Images
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Complex HuMAP2_04615 has an average edge precision of 0.097 which is ranked 6940 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| POFUT2 | HuMAP2_00668 HuMAP2_03238 HuMAP2_04615 HuMAP2_04935 HuMAP2_06314 HuMAP2_06768 |
| CORO1C | HuMAP2_03582 HuMAP2_04442 HuMAP2_04615 HuMAP2_06976 |
| SSH2 | HuMAP2_04615 |
| PPP1R9B | HuMAP2_04615 HuMAP2_05328 HuMAP2_05394 HuMAP2_06738 |
| SYNPO | HuMAP2_02178 HuMAP2_03582 HuMAP2_04615 HuMAP2_05394 HuMAP2_05638 |
| CTTN | HuMAP2_00558 HuMAP2_03582 HuMAP2_04615 |
| PLEKHG3 | HuMAP2_04615 HuMAP2_05394 |