hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04626
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RAB5C | Ras-related protein Rab-5C (L1880) (RAB5L) | UniProt NCBI |
| GNAT3 | Guanine nucleotide-binding protein G(t) subunit alpha-3 (Gustducin alpha-3 chain) | UniProt NCBI |
| RAB5B | Ras-related protein Rab-5B | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4301 | 0.000146652290714 | 0.666666666667 | RAB5C RAB5B | Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells |
| KEGG:04962 | 0.000348719274028 | 0.666666666667 | RAB5C RAB5B | Vasopressin-regulated water reabsorption |
| KEGG:05146 | 0.00159284054118 | 0.666666666667 | RAB5C RAB5B | Amoebiasis |
| KEGG:04145 | 0.00402657539006 | 0.666666666667 | RAB5C RAB5B | Phagosome |
| KEGG:05152 | 0.00497142990217 | 0.666666666667 | RAB5C RAB5B | Tuberculosis |
| REAC:R-HSA-8854214 | 0.00603484671946 | 0.666666666667 | RAB5C RAB5B | TBC/RABGAPs |
| KEGG:04014 | 0.00747836674868 | 0.666666666667 | RAB5C RAB5B | Ras signaling pathway |
| WP:WP4223 | 0.0113696258401 | 0.666666666667 | RAB5C RAB5B | Ras Signaling |
| KEGG:04144 | 0.0117748506163 | 0.666666666667 | RAB5C RAB5B | Endocytosis |
| REAC:R-HSA-8873719 | 0.0126269885924 | 0.666666666667 | RAB5C RAB5B | RAB geranylgeranylation |
| REAC:R-HSA-8876198 | 0.0238137546255 | 0.666666666667 | RAB5C RAB5B | RAB GEFs exchange GTP for GDP on RABs |
| GO:0048227 | 0.0378589948753 | 0.666666666667 | RAB5C RAB5B | plasma membrane to endosome transport |
| REAC:R-HSA-9007101 | 0.0444303896492 | 0.666666666667 | RAB5C RAB5B | Rab regulation of trafficking |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RAB5C | RAB5B | 0.032 | 0.246 | hein_WMM bioplex_WMM youn_WMM hein (RAB5B,RAB5C) gupta_WMM treiber_WMM |
| GNAT3 | RAB5C | 0.029 | 0.23 | bioplex (RAB5C) bioplex_WMM boldt boldt_WMM |
Images
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Complex HuMAP2_04626 has an average edge precision of 0.238 which is ranked 5563 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RAB5C | HuMAP2_01779 HuMAP2_02250 HuMAP2_04626 HuMAP2_05110 HuMAP2_05570 |
| GNAT3 | HuMAP2_00508 HuMAP2_04626 HuMAP2_04946 HuMAP2_05570 |
| RAB5B | HuMAP2_02250 HuMAP2_04626 HuMAP2_05570 HuMAP2_05778 |