hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04627
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CDKN2AIP | CDKN2A-interacting protein (Collaborator of ARF) | UniProt NCBI |
| PSPC1 | Paraspeckle component 1 (Paraspeckle protein 1) | UniProt NCBI |
| NONO | Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (55 kDa nuclear protein) (DNA-binding p52/p100 complex, 52 kDa subunit) (NMT55) (p54(nrb)) (p54nrb) | UniProt NCBI |
| XRN2 | 5'-3' exoribonuclease 2 (EC 3.1.13.-) (DHM1-like protein) (DHP protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7285 | 0.000180886312261 | 0.5 | NONO PSPC1 | HEXIM1-DNA-PK-paraspeckle components-ribonucleoprotein complex |
| WP:WP411 | 0.0128777248997 | 0.5 | XRN2 NONO | mRNA Processing |
| WP:WP3594 | 0.021597405556 | 0.5 | NONO PSPC1 | Circadian rhythm related genes |
| MIRNA:hsa-miR-606 | 0.0291936286934 | 0.5 | XRN2 PSPC1 | hsa-miR-606 |
| CORUM:330 | 0.0499140284799 | 0.25 | NONO | PSF-p54(nrb) complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| XRN2 | CDKN2AIP | 0.963 | 0.871 | hein_WMM youn (XRN2) bioplex_WMM youn_WMM hein (CDKN2AIP) gupta_WMM fraction |
| PSPC1 | XRN2 | 0.936 | 0.85 | youn (XRN2) boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| NONO | XRN2 | 0.722 | 0.732 | youn (XRN2) bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| PSPC1 | NONO | 0.482 | 0.612 | hein_WMM bioplex (NONO) bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| PSPC1 | CDKN2AIP | 0.0 | 0.007 | youn_WMM gupta_WMM fraction |
| NONO | CDKN2AIP | 0.0 | 0.0 | bioplex_WMM fraction |
Images
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Complex HuMAP2_04627 has an average edge precision of 0.512 which is ranked 2434 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CDKN2AIP | HuMAP2_02593 HuMAP2_04627 HuMAP2_05678 |
| PSPC1 | HuMAP2_00096 HuMAP2_02074 HuMAP2_04627 |
| NONO | HuMAP2_02168 HuMAP2_04627 |
| XRN2 | HuMAP2_02593 HuMAP2_04627 HuMAP2_05678 |