hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04632
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IGF2BP1 | Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1) | UniProt NCBI |
| IGF2BP2 | Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62) (IGF-II mRNA-binding protein 2) (VICKZ family member 2) | UniProt NCBI |
| PABPC4 | Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP) | UniProt NCBI |
| LARP1 | La-related protein 1 (La ribonucleoprotein domain family member 1) | UniProt NCBI |
| ANKRD17 | Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) | UniProt NCBI |
| LARP1B | La-related protein 1B (La ribonucleoprotein domain family member 1B) (La ribonucleoprotein domain family member 2) (La-related protein 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-428359 | 6.65030189148e-05 | 0.333333333333 | IGF2BP1 IGF2BP2 | Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA |
| GO:0003730 | 0.000417891539136 | 0.666666666667 | LARP1 IGF2BP1 IGF2BP2 PABPC4 | mRNA 3'-UTR binding |
| GO:0048027 | 0.0032070828615 | 0.5 | IGF2BP1 IGF2BP2 LARP1 | mRNA 5'-UTR binding |
| GO:0003729 | 0.0321337430886 | 0.666666666667 | LARP1 IGF2BP1 IGF2BP2 PABPC4 | mRNA binding |
| GO:0003723 | 0.0386338629612 | 1.0 | LARP1B LARP1 PABPC4 IGF2BP1 ANKRD17 IGF2BP2 | RNA binding |
| GO:0010494 | 0.0472791215337 | 0.5 | IGF2BP1 PABPC4 LARP1 | cytoplasmic stress granule |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| LARP1 | PABPC4 | 0.849 | 0.79 | hein_WMM bioplex_WMM gupta_WMM fraction treiber_WMM |
| LARP1 | IGF2BP1 | 0.735 | 0.738 | hein_WMM youn (IGF2BP1) bioplex_WMM gupta_WMM fraction treiber_WMM |
| IGF2BP2 | IGF2BP1 | 0.5 | 0.621 | youn (IGF2BP1,IGF2BP2) bioplex_WMM youn_WMM Malo gupta_WMM fraction treiber_WMM |
| ANKRD17 | PABPC4 | 0.321 | 0.512 | youn (ANKRD17) bioplex_WMM youn_WMM gupta_WMM fraction |
| IGF2BP1 | PABPC4 | 0.084 | 0.348 | youn (IGF2BP1) bioplex_WMM youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| LARP1 | LARP1B | 0.079 | 0.353 | hein_WMM bioplex (LARP1B) bioplex_WMM gupta_WMM |
| LARP1B | PABPC4 | 0.015 | 0.138 | bioplex (LARP1B) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| LARP1B | ANKRD17 | 0.006 | 0.006 | youn (ANKRD17) bioplex_WMM youn_WMM gupta_WMM |
| IGF2BP2 | ANKRD17 | 0.006 | 0.009 | youn (ANKRD17,IGF2BP2) bioplex_WMM youn_WMM gupta_WMM |
| IGF2BP1 | ANKRD17 | 0.006 | 0.007 | youn (ANKRD17,IGF2BP1) bioplex_WMM youn_WMM gupta_WMM |
| LARP1 | ANKRD17 | 0.005 | 0.011 | hein_WMM youn (ANKRD17) bioplex_WMM gupta_WMM |
| IGF2BP2 | LARP1B | 0.004 | 0.014 | youn (IGF2BP2) bioplex_WMM youn_WMM gupta_WMM |
| LARP1 | IGF2BP2 | 0.0 | 0.01 | youn (IGF2BP2) bioplex_WMM gupta_WMM treiber_WMM |
| IGF2BP1 | LARP1B | 0.0 | 0.008 | youn (IGF2BP1) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| IGF2BP2 | PABPC4 | 0.0 | 0.01 | youn (IGF2BP2) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
Images
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Complex HuMAP2_04632 has an average edge precision of 0.238 which is ranked 5555 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IGF2BP1 | HuMAP2_00556 HuMAP2_03425 HuMAP2_04560 HuMAP2_04632 HuMAP2_06751 |
| IGF2BP2 | HuMAP2_00556 HuMAP2_00999 HuMAP2_04632 HuMAP2_06202 HuMAP2_06751 |
| PABPC4 | HuMAP2_04393 HuMAP2_04632 HuMAP2_05552 HuMAP2_05559 HuMAP2_05734 HuMAP2_05864 |
| LARP1 | HuMAP2_00428 HuMAP2_04560 HuMAP2_04632 HuMAP2_05552 HuMAP2_05734 |
| ANKRD17 | HuMAP2_01582 HuMAP2_04632 HuMAP2_06735 |
| LARP1B | HuMAP2_00870 HuMAP2_02213 HuMAP2_04632 HuMAP2_05000 |