hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04636
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| LYRM7 | Complex III assembly factor LYRM7 (LYR motif-containing protein 7) | UniProt NCBI |
| SDHAF1 | Succinate dehydrogenase assembly factor 1, mitochondrial (SDH assembly factor 1) (SDHAF1) (LYR motif-containing protein 8) | UniProt NCBI |
| NDUFAB1 | Acyl carrier protein, mitochondrial (ACP) (CI-SDAP) (NADH-ubiquinone oxidoreductase 9.6 kDa subunit) | UniProt NCBI |
| OXSM | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial (EC 2.3.1.41) (Beta-ketoacyl-ACP synthase) | UniProt NCBI |
| LYRM2 | LYR motif-containing protein 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0001285 | 0.0308081945037 | 0.4 | LYRM7 SDHAF1 | Spastic tetraparesis |
| HP:0000544 | 0.0360671162807 | 0.4 | LYRM7 SDHAF1 | External ophthalmoplegia |
| KEGG:00780 | 0.0479450706651 | 0.2 | OXSM | Biotin metabolism |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NDUFAB1 | LYRM2 | 0.529 | 0.634 | bioplex (LYRM2,NDUFAB1) bioplex_WMM |
| NDUFAB1 | LYRM7 | 0.41 | 0.569 | bioplex (NDUFAB1) bioplex_WMM |
| NDUFAB1 | SDHAF1 | 0.366 | 0.543 | bioplex (NDUFAB1) bioplex_WMM |
| NDUFAB1 | OXSM | 0.069 | 0.349 | bioplex (NDUFAB1) bioplex_WMM |
| OXSM | LYRM2 | 0.031 | 0.236 | bioplex (LYRM2) bioplex_WMM |
| LYRM7 | SDHAF1 | 0.009 | 0.098 | bioplex_WMM WMM_only |
| LYRM2 | SDHAF1 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| OXSM | LYRM7 | 0.008 | 0.058 | bioplex_WMM WMM_only |
| OXSM | SDHAF1 | 0.008 | 0.04 | bioplex_WMM WMM_only |
| LYRM7 | LYRM2 | 0.008 | 0.028 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04636 has an average edge precision of 0.262 which is ranked 5192 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| LYRM7 | HuMAP2_00017 HuMAP2_04636 |
| SDHAF1 | HuMAP2_00017 HuMAP2_01581 HuMAP2_04636 HuMAP2_05881 |
| NDUFAB1 | HuMAP2_00017 HuMAP2_04128 HuMAP2_04636 |
| OXSM | HuMAP2_00017 HuMAP2_00619 HuMAP2_04636 |
| LYRM2 | HuMAP2_00017 HuMAP2_00619 HuMAP2_04128 HuMAP2_04636 |