hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04650
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RALGAPA1 | Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240) | UniProt NCBI |
| RALGAPA2 | Ral GTPase-activating protein subunit alpha-2 (250 kDa substrate of Akt) (AS250) (p220) | UniProt NCBI |
| DPH7 | Diphthine methyltransferase (EC 3.1.1.97) (Diphthamide biosynthesis protein 7) (WD repeat-containing protein 85) | UniProt NCBI |
| RALGAPB | Ral GTPase-activating protein subunit beta (p170) | UniProt NCBI |
| NKIRAS2 | NF-kappa-B inhibitor-interacting Ras-like protein 2 (I-kappa-B-interacting Ras-like protein 2) (Kappa B-Ras protein 2) (KappaB-Ras2) | UniProt NCBI |
| GFOD2 | Glucose-fructose oxidoreductase domain-containing protein 2 (EC 1.-.-.-) | UniProt NCBI |
| GFOD1 | Glucose-fructose oxidoreductase domain-containing protein 1 (EC 1.-.-.-) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:026010_03 | 0.00810501459852 | 0.428571428571 | RALGAPA2 GFOD2 GFOD1 | liver; bile duct cells[Uncertain,High] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RALGAPA2 | GFOD1 | 1.0 | 0.949 | bioplex (GFOD1) bioplex_WMM |
| GFOD2 | GFOD1 | 1.0 | 0.949 | bioplex (GFOD1) bioplex_WMM |
| RALGAPA1 | GFOD1 | 1.0 | 0.949 | bioplex (GFOD1) bioplex_WMM |
| RALGAPB | GFOD1 | 1.0 | 0.949 | bioplex (GFOD1) bioplex_WMM |
| RALGAPA2 | NKIRAS2 | 0.991 | 0.909 | bioplex (NKIRAS2) bioplex_WMM |
| RALGAPA1 | NKIRAS2 | 0.977 | 0.893 | bioplex (NKIRAS2) bioplex_WMM boldt_WMM |
| RALGAPB | NKIRAS2 | 0.929 | 0.845 | bioplex (NKIRAS2) bioplex_WMM boldt_WMM |
| NKIRAS2 | GFOD1 | 0.559 | 0.65 | bioplex (GFOD1,NKIRAS2) bioplex_WMM |
| NKIRAS2 | GFOD2 | 0.532 | 0.637 | bioplex (NKIRAS2) bioplex_WMM |
| RALGAPA2 | DPH7 | 0.029 | 0.233 | bioplex (DPH7) bioplex_WMM |
| DPH7 | RALGAPB | 0.012 | 0.147 | bioplex (DPH7) bioplex_WMM |
| RALGAPA2 | RALGAPB | 0.012 | 0.146 | bioplex_WMM WMM_only |
| RALGAPB | RALGAPA1 | 0.011 | 0.136 | bioplex_WMM gupta_WMM WMM_only boldt_WMM |
| RALGAPA1 | GFOD2 | 0.011 | 0.14 | bioplex_WMM WMM_only |
| RALGAPA2 | RALGAPA1 | 0.011 | 0.144 | bioplex_WMM WMM_only |
| RALGAPA2 | GFOD2 | 0.01 | 0.134 | bioplex_WMM WMM_only |
| RALGAPB | GFOD2 | 0.01 | 0.126 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04650 has an average edge precision of 0.526 which is ranked 2367 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RALGAPA1 | HuMAP2_03389 HuMAP2_04650 HuMAP2_05589 |
| RALGAPA2 | HuMAP2_02413 HuMAP2_03389 HuMAP2_03770 HuMAP2_04650 HuMAP2_05589 |
| DPH7 | HuMAP2_02413 HuMAP2_04650 |
| RALGAPB | HuMAP2_03389 HuMAP2_04650 HuMAP2_05589 |
| NKIRAS2 | HuMAP2_03389 HuMAP2_04650 HuMAP2_05589 |
| GFOD2 | HuMAP2_03389 HuMAP2_04650 HuMAP2_04710 HuMAP2_05589 |
| GFOD1 | HuMAP2_03389 HuMAP2_03770 HuMAP2_04650 HuMAP2_04710 HuMAP2_05589 |