hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04660
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| VPS36 | Vacuolar protein-sorting-associated protein 36 (ELL-associated protein of 45 kDa) (ESCRT-II complex subunit VPS36) | UniProt NCBI |
| TIMM8B | Mitochondrial import inner membrane translocase subunit Tim8 B (DDP-like protein) (Deafness dystonia protein 2) | UniProt NCBI |
| TIMM8A | Mitochondrial import inner membrane translocase subunit Tim8 A (Deafness dystonia protein 1) (X-linked deafness dystonia protein) | UniProt NCBI |
| TIMM13 | Mitochondrial import inner membrane translocase subunit Tim13 | UniProt NCBI |
| BANF1 | Barrier-to-autointegration factor (Breakpoint cluster region protein 1) [Cleaved into: Barrier-to-autointegration factor, N-terminally processed] | UniProt NCBI |
| ABHD11 | Protein ABHD11 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 11) (Abhydrolase domain-containing protein 11) (Williams-Beuren syndrome chromosomal region 21 protein) | UniProt NCBI |
| YBEY | Endoribonuclease YbeY (EC 3.1.-.-) | UniProt NCBI |
| STPG3 | Protein STPG3 (Sperm-tail PG-rich repeat-containing protein 3) | UniProt NCBI |
| PDYN | Proenkephalin-B (Beta-neoendorphin-dynorphin) (Preprodynorphin) [Cleaved into: Alpha-neoendorphin; Beta-neoendorphin; Big dynorphin (Big Dyn); Dynorphin A(1-17) (Dyn-A17) (Dynorphin A); Dynorphin A(1-13); Dynorphin A(1-8); Leu-enkephalin; Rimorphin (Dynorphin B) (Dyn-B) (Dynorphin B(1-13)); Leumorphin (Dynorphin B-29)] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6452 | 1.34129279418e-05 | 0.222222222222 | TIMM8A TIMM13 | TIMM8A-TIMM13 complex |
| CORUM:7198 | 4.02261743042e-05 | 0.222222222222 | TIMM8A TIMM13 | TIMM8A-TIMM13-TIMM23 complex |
| GO:0072321 | 0.000913516286731 | 0.333333333333 | TIMM13 TIMM8B TIMM8A | chaperone-mediated protein transport |
| REAC:R-HSA-1268020 | 0.0010222833809 | 0.333333333333 | TIMM13 TIMM8B TIMM8A | Mitochondrial protein import |
| REAC:R-HSA-9609507 | 0.0147875834949 | 0.333333333333 | TIMM13 TIMM8B TIMM8A | Protein localization |
| MIRNA:hsa-miR-6743-3p | 0.0174716460599 | 0.222222222222 | PDYN TIMM8A | hsa-miR-6743-3p |
| CORUM:1989 | 0.0249698419797 | 0.111111111111 | BANF1 | BANF1 homodimer protein |
| CORUM:6148 | 0.0249698419797 | 0.111111111111 | BANF1 | BAFL-BAF complex |
| CORUM:6147 | 0.0499262710315 | 0.111111111111 | BANF1 | BAFL-BAF-LAP2beta complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TIMM8B | TIMM13 | 0.952 | 0.858 | hein_WMM bioplex_WMM Guru boldt Malo fraction boldt_WMM |
| PDYN | TIMM8B | 0.945 | 0.857 | bioplex (PDYN) bioplex_WMM |
| PDYN | TIMM13 | 0.303 | 0.497 | bioplex (PDYN) bioplex_WMM |
| PDYN | TIMM8A | 0.091 | 0.354 | bioplex (PDYN) bioplex_WMM |
| TIMM8A | TIMM13 | 0.077 | 0.352 | hein_WMM bioplex_WMM boldt fraction boldt_WMM |
| TIMM13 | STPG3 | 0.069 | 0.347 | bioplex (STPG3) bioplex_WMM |
| VPS36 | TIMM8A | 0.031 | 0.24 | fraction |
| BANF1 | TIMM13 | 0.025 | 0.216 | bioplex_WMM fraction |
| ABHD11 | YBEY | 0.022 | 0.209 | bioplex (YBEY) bioplex_WMM |
| TIMM8B | YBEY | 0.02 | 0.186 | bioplex (YBEY) bioplex_WMM |
| TIMM8A | YBEY | 0.02 | 0.185 | bioplex (YBEY) bioplex_WMM |
| TIMM13 | YBEY | 0.019 | 0.182 | bioplex (YBEY) bioplex_WMM |
| TIMM8B | TIMM8A | 0.019 | 0.184 | bioplex_WMM boldt boldt_WMM |
| VPS36 | TIMM13 | 0.011 | 0.14 | bioplex (VPS36) fraction |
| TIMM8A | STPG3 | 0.008 | 0.044 | bioplex (STPG3) bioplex_WMM |
| TIMM8B | ABHD11 | 0.007 | 0.011 | bioplex_WMM WMM_only |
| TIMM8A | ABHD11 | 0.007 | 0.01 | bioplex_WMM WMM_only |
| TIMM13 | ABHD11 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| BANF1 | VPS36 | 0.007 | 0.01 | bioplex_WMM WMM_only |
| BANF1 | TIMM8A | 0.007 | 0.006 | bioplex_WMM WMM_only |
| BANF1 | TIMM8B | 0.007 | 0.006 | bioplex_WMM WMM_only |
| BANF1 | YBEY | 0.006 | 0.006 | bioplex_WMM WMM_only |
| BANF1 | PDYN | 0.006 | 0.009 | bioplex (PDYN) bioplex_WMM |
| TIMM8B | STPG3 | 0.005 | 0.009 | bioplex (STPG3) |
Images
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Complex HuMAP2_04660 has an average edge precision of 0.205 which is ranked 6102 out of all 6965 complexes.
Related Complexes