hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04662
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EPB41L3 | Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) [Cleaved into: Band 4.1-like protein 3, N-terminally processed] | UniProt NCBI |
| KRT222 | Keratin-like protein KRT222 (Keratin-222) (Keratin-222 pseudogene) | UniProt NCBI |
| CEP164 | Centrosomal protein of 164 kDa (Cep164) | UniProt NCBI |
| RBM33 | RNA-binding protein 33 (Proline-rich protein 8) (RNA-binding motif protein 33) | UniProt NCBI |
| EPB41 | Protein 4.1 (P4.1) (4.1R) (Band 4.1) (EPB4.1) | UniProt NCBI |
| EPB41L2 | Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4148 | 1.47484434565e-05 | 0.5 | EPB41L3 EPB41 EPB41L2 | Splicing factor NOVA regulated synaptic proteins |
| REAC:R-HSA-6794361 | 0.00013845803743 | 0.5 | EPB41L3 EPB41 EPB41L2 | Neurexins and neuroligins |
| REAC:R-HSA-6794362 | 0.000502143964773 | 0.5 | EPB41L3 EPB41 EPB41L2 | Protein-protein interactions at synapses |
| REAC:R-HSA-112316 | 0.0370544697669 | 0.5 | EPB41L3 EPB41 EPB41L2 | Neuronal System |
| CORUM:6254 | 0.0499726005494 | 0.166666666667 | EPB41 | GPC-4.1R-p55 complex |
| CORUM:6518 | 0.0499726005494 | 0.166666666667 | CEP164 | CEP164-TTBK2 complex |
| CORUM:6519 | 0.0499726005494 | 0.166666666667 | CEP164 | CCDC92-CEP164 complex |
| CORUM:6531 | 0.0499726005494 | 0.166666666667 | CEP164 | CEP164-DZIP1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KRT222 | EPB41L2 | 0.943 | 0.856 | bioplex () boldt_WMM |
| EPB41L3 | KRT222 | 0.931 | 0.846 | bioplex () |
| EPB41L3 | EPB41L2 | 0.489 | 0.616 | bioplex (EPB41L2) bioplex_WMM youn_WMM gupta_WMM boldt_WMM |
| KRT222 | EPB41 | 0.137 | 0.408 | bioplex () |
| EPB41L2 | EPB41 | 0.031 | 0.238 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| KRT222 | CEP164 | 0.03 | 0.236 | bioplex () |
| RBM33 | EPB41L3 | 0.029 | 0.232 | youn_WMM gupta_WMM fraction |
| EPB41L3 | EPB41 | 0.028 | 0.231 | bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| RBM33 | EPB41L2 | 0.013 | 0.147 | youn_WMM gupta_WMM fraction |
| EPB41 | CEP164 | 0.007 | 0.009 | youn_WMM gupta_WMM WMM_only bioplex_WMM |
| EPB41L3 | CEP164 | 0.007 | 0.005 | gupta (CEP164) youn_WMM gupta_WMM bioplex_WMM |
| RBM33 | EPB41 | 0.007 | 0.003 | youn_WMM gupta_WMM WMM_only |
| EPB41L2 | CEP164 | 0.007 | 0.004 | youn_WMM gupta_WMM WMM_only bioplex_WMM |
| RBM33 | CEP164 | 0.006 | 0.001 | gupta (CEP164) youn_WMM gupta_WMM |
Images
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Complex HuMAP2_04662 has an average edge precision of 0.274 which is ranked 4971 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| EPB41L3 | HuMAP2_02663 HuMAP2_04662 HuMAP2_05874 |
| KRT222 | HuMAP2_02663 HuMAP2_03454 HuMAP2_04662 HuMAP2_05874 |
| CEP164 | HuMAP2_04662 |
| RBM33 | HuMAP2_01249 HuMAP2_04662 |
| EPB41 | HuMAP2_04662 HuMAP2_05874 |
| EPB41L2 | HuMAP2_03454 HuMAP2_04662 HuMAP2_05874 |