hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04664
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| WDR48 | WD repeat-containing protein 48 (USP1-associated factor 1) (WD repeat endosomal protein) (p80) | UniProt NCBI |
| RAD51AP1 | RAD51-associated protein 1 (RAD51-interacting protein) | UniProt NCBI |
| USP1 | Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (hUBP) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3176 | 3.35600554376e-06 | 0.666666666667 | WDR48 USP1 | USP1-UAF1 complex |
| CORUM:6638 | 3.35600554376e-06 | 0.666666666667 | WDR48 USP1 | USP1-UAF1 complex |
| CORUM:6521 | 7.04603414803e-05 | 0.666666666667 | WDR48 USP1 | Akt-PHLPP1-PHLPP2-FANCI-FANCD2-USP1-UAF1 complex |
| KEGG:03460 | 0.00052554917631 | 0.666666666667 | WDR48 USP1 | Fanconi anemia pathway |
| GO:0036297 | 0.0015707980909 | 1.0 | WDR48 RAD51AP1 USP1 | interstrand cross-link repair |
| REAC:R-HSA-73894 | 0.00245537461814 | 1.0 | WDR48 RAD51AP1 USP1 | DNA Repair |
| REAC:R-HSA-110314 | 0.00290884705451 | 0.666666666667 | WDR48 USP1 | Recognition of DNA damage by PCNA-containing replication complex |
| REAC:R-HSA-6783310 | 0.00397787610966 | 0.666666666667 | WDR48 USP1 | Fanconi Anemia Pathway |
| REAC:R-HSA-73893 | 0.00722314394396 | 0.666666666667 | WDR48 USP1 | DNA Damage Bypass |
| WP:WP3596 | 0.0357037760272 | 0.333333333333 | USP1 | miR-517 relationship with ARCN1 and USP1 |
| CORUM:6636 | 0.0499776345577 | 0.333333333333 | WDR48 | USP12-UAF1 complex |
| CORUM:6637 | 0.0499776345577 | 0.333333333333 | WDR48 | USP46-UAF1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| WDR48 | USP1 | 0.18 | 0.437 | hein_WMM bioplex (USP1) bioplex_WMM hein (WDR48) boldt_WMM |
| WDR48 | RAD51AP1 | 0.073 | 0.354 | bioplex (RAD51AP1) bioplex_WMM |
| USP1 | RAD51AP1 | 0.0 | 0.01 | bioplex (RAD51AP1) bioplex_WMM |
Images
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Complex HuMAP2_04664 has an average edge precision of 0.267 which is ranked 5096 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| WDR48 | HuMAP2_01079 HuMAP2_01858 HuMAP2_04664 HuMAP2_05585 HuMAP2_06059 |
| RAD51AP1 | HuMAP2_01079 HuMAP2_04664 HuMAP2_06059 |
| USP1 | HuMAP2_01079 HuMAP2_04664 HuMAP2_06059 |