hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04680
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RAE1 | mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41) | UniProt NCBI |
| ALDOA | Fructose-bisphosphate aldolase A (EC 4.1.2.13) (Lung cancer antigen NY-LU-1) (Muscle-type aldolase) | UniProt NCBI |
| ALDOC | Fructose-bisphosphate aldolase C (EC 4.1.2.13) (Brain-type aldolase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-70171 | 2.05735546476e-05 | 1.0 | RAE1 ALDOA ALDOC | Glycolysis |
| REAC:R-HSA-70326 | 3.98163024387e-05 | 1.0 | RAE1 ALDOA ALDOC | Glucose metabolism |
| KEGG:00030 | 0.000181602388379 | 0.666666666667 | ALDOA ALDOC | Pentose phosphate pathway |
| KEGG:00051 | 0.000236130222292 | 0.666666666667 | ALDOA ALDOC | Fructose and mannose metabolism |
| KEGG:00010 | 0.00087223886567 | 0.666666666667 | ALDOA ALDOC | Glycolysis / Gluconeogenesis |
| WP:WP534 | 0.000905695914221 | 0.666666666667 | ALDOA ALDOC | Glycolysis and Gluconeogenesis |
| KEGG:01230 | 0.00110943942397 | 0.666666666667 | ALDOA ALDOC | Biosynthesis of amino acids |
| REAC:R-HSA-71387 | 0.00133225455863 | 1.0 | RAE1 ALDOA ALDOC | Metabolism of carbohydrates |
| KEGG:04066 | 0.00220707183162 | 0.666666666667 | ALDOA ALDOC | HIF-1 signaling pathway |
| KEGG:01200 | 0.00287006078872 | 0.666666666667 | ALDOA ALDOC | Carbon metabolism |
| REAC:R-HSA-70263 | 0.00290884705451 | 0.666666666667 | ALDOA ALDOC | Gluconeogenesis |
| WP:WP4018 | 0.00302048413579 | 0.666666666667 | ALDOA ALDOC | Pathways in clear cell renal cell carcinoma |
| GO:0004332 | 0.00405722906526 | 0.666666666667 | ALDOA ALDOC | fructose-bisphosphate aldolase activity |
| GO:0006096 | 0.0117851633362 | 1.0 | RAE1 ALDOA ALDOC | glycolytic process |
| GO:0006757 | 0.0121736852044 | 1.0 | RAE1 ALDOA ALDOC | ATP generation from ADP |
| MIRNA:hsa-miR-454-5p | 0.0123374324525 | 0.666666666667 | ALDOA ALDOC | hsa-miR-454-5p |
| GO:0046031 | 0.0129761581422 | 1.0 | RAE1 ALDOA ALDOC | ADP metabolic process |
| GO:0009179 | 0.0138131421388 | 1.0 | RAE1 ALDOA ALDOC | purine ribonucleoside diphosphate metabolic process |
| GO:0009135 | 0.0138131421388 | 1.0 | RAE1 ALDOA ALDOC | purine nucleoside diphosphate metabolic process |
| GO:0009185 | 0.0146853637429 | 1.0 | RAE1 ALDOA ALDOC | ribonucleoside diphosphate metabolic process |
| GO:0006165 | 0.0151349156943 | 1.0 | RAE1 ALDOA ALDOC | nucleoside diphosphate phosphorylation |
| GO:0046939 | 0.0155935495032 | 1.0 | RAE1 ALDOA ALDOC | nucleotide phosphorylation |
| GO:0009132 | 0.0180261250619 | 1.0 | RAE1 ALDOA ALDOC | nucleoside diphosphate metabolic process |
| GO:0016832 | 0.0283955176165 | 0.666666666667 | ALDOA ALDOC | aldehyde-lyase activity |
| GO:0006090 | 0.0288576025313 | 1.0 | RAE1 ALDOA ALDOC | pyruvate metabolic process |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ALDOC | RAE1 | 0.975 | 0.887 | bioplex_WMM fraction |
| ALDOA | ALDOC | 0.937 | 0.85 | hein_WMM bioplex (ALDOA,ALDOC) bioplex_WMM hein (ALDOA) fraction treiber_WMM |
| ALDOA | RAE1 | 0.228 | 0.468 | bioplex (RAE1) bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_04680 has an average edge precision of 0.735 which is ranked 1235 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RAE1 | HuMAP2_03109 HuMAP2_04230 HuMAP2_04680 HuMAP2_05544 |
| ALDOA | HuMAP2_01418 HuMAP2_01883 HuMAP2_03109 HuMAP2_04680 HuMAP2_06632 HuMAP2_06652 |
| ALDOC | HuMAP2_01418 HuMAP2_03109 HuMAP2_04230 HuMAP2_04680 HuMAP2_06764 |