hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04695
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MAU2 | MAU2 chromatid cohesion factor homolog (MAU-2) (Cohesin loading complex subunit SCC4 homolog) | UniProt NCBI |
| NIPBL | Nipped-B-like protein (Delangin) (SCC2 homolog) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2470946 | 7.54165558069e-05 | 1.0 | MAU2 NIPBL | Cohesin Loading onto Chromatin |
| REAC:R-HSA-68884 | 0.000152509035076 | 1.0 | MAU2 NIPBL | Mitotic Telophase/Cytokinesis |
| GO:0032116 | 0.000450823411379 | 1.0 | MAU2 NIPBL | SMC loading complex |
| GO:0090694 | 0.000450823411379 | 1.0 | MAU2 NIPBL | Scc2-Scc4 cohesin loading complex |
| GO:0071921 | 0.00450823411379 | 1.0 | MAU2 NIPBL | cohesin loading |
| GO:0034085 | 0.00946729163895 | 1.0 | MAU2 NIPBL | establishment of sister chromatid cohesion |
| GO:0034086 | 0.029754345151 | 1.0 | MAU2 NIPBL | maintenance of sister chromatid cohesion |
| GO:0034088 | 0.029754345151 | 1.0 | MAU2 NIPBL | maintenance of mitotic sister chromatid cohesion |
| HP:0005565 | 0.0497341708567 | 0.5 | NIPBL | Reduced renal corticomedullary differentiation |
| HP:0031228 | 0.0497341708567 | 0.5 | NIPBL | Abnormal incisura morphology |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MAU2 | NIPBL | 0.994 | 0.918 | hein_WMM bioplex_WMM hein (MAU2) Malo fraction |
Images
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Complex HuMAP2_04695 has an average edge precision of 0.918 which is ranked 482 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MAU2 | HuMAP2_02622 HuMAP2_04695 |
| NIPBL | HuMAP2_02622 HuMAP2_04695 |