hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_04697

Confidence: Medium

Genename	Protein Name	Links
CEP350	Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa)	UniProt NCBI
PCNT	Pericentrin (Kendrin) (Pericentrin-B)	UniProt NCBI
PPP2R3C	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (Protein phosphatase subunit G5PR) (Rhabdomyosarcoma antigen MU-RMS-40.6A/6C)	UniProt NCBI
CEP131	Centrosomal protein of 131 kDa (5-azacytidine-induced protein 1) (Pre-acrosome localization protein 1)	UniProt NCBI
NIN	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein)	UniProt NCBI
C2CD3	C2 domain-containing protein 3	UniProt NCBI
FAM81B	Protein FAM81B	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0044450	8.4365692279e-05	0.714285714286	NIN CEP131 CEP350 PCNT C2CD3	microtubule organizing center part
GO:0005813	0.000264860200694	0.857142857143	PCNT PPP2R3C CEP350 C2CD3 NIN CEP131	centrosome
GO:0005815	0.00138247424367	0.857142857143	PCNT PPP2R3C CEP350 C2CD3 NIN CEP131	microtubule organizing center
REAC:R-HSA-5620912	0.0014444070504	0.428571428571	CEP131 PCNT C2CD3	Anchoring of the basal body to the plasma membrane
GO:0005814	0.00316523412735	0.571428571429	NIN CEP350 PCNT C2CD3	centriole
GO:0034451	0.00727854676446	0.428571428571	CEP131 PCNT C2CD3	centriolar satellite
REAC:R-HSA-5617833	0.0116992025039	0.428571428571	CEP131 PCNT C2CD3	Cilium Assembly
GO:0015630	0.0197202111589	0.857142857143	PCNT PPP2R3C CEP350 C2CD3 NIN CEP131	microtubule cytoskeleton
WP:WP4656	0.0260504484155	0.285714285714	NIN PCNT	Joubert Syndrome
GO:0000226	0.0271422741221	0.714285714286	NIN C2CD3 CEP131 PCNT PPP2R3C	microtubule cytoskeleton organization
REAC:R-HSA-1852241	0.0359967876154	0.428571428571	CEP131 PCNT C2CD3	Organelle biogenesis and maintenance

Protein 1	Protein 2	Score	Precision	Evidence
PPP2R3C	CEP350	0.09	0.355	hein_WMM bioplex_WMM hein (PPP2R3C) gupta_WMM boldt_WMM
CEP131	CEP350	0.075	0.357	hein_WMM bioplex_WMM youn_WMM hein (CEP131) gupta_WMM boldt_WMM
CEP131	NIN	0.059	0.328	hein_WMM gupta (NIN) youn_WMM hein (CEP131) gupta_WMM
CEP131	C2CD3	0.055	0.305	hein_WMM youn_WMM hein (CEP131) gupta_WMM
CEP131	PCNT	0.038	0.265	hein_WMM bioplex_WMM youn_WMM hein (PCNT) gupta_WMM
CEP131	PPP2R3C	0.024	0.214	hein_WMM hein (PPP2R3C) gupta_WMM
PCNT	FAM81B	0.021	0.186	bioplex (FAM81B) bioplex_WMM
NIN	CEP350	0.008	0.09	hein_WMM gupta (NIN) youn_WMM gupta_WMM
CEP350	C2CD3	0.008	0.081	hein_WMM youn_WMM gupta_WMM WMM_only
PCNT	C2CD3	0.007	0.01	hein_WMM youn_WMM gupta_WMM WMM_only
NIN	C2CD3	0.007	0.004	hein_WMM gupta_WMM WMM_only
PPP2R3C	C2CD3	0.007	0.002	hein_WMM gupta_WMM WMM_only
NIN	PPP2R3C	0.007	0.005	gupta_WMM WMM_only
PCNT	PPP2R3C	0.007	0.003	hein_WMM gupta_WMM WMM_only
PCNT	CEP350	0.006	0.003	hein_WMM youn_WMM gupta_WMM WMM_only boldt_WMM
NIN	PCNT	0.005	0.012	bioplex_WMM gupta (NIN) youn_WMM gupta_WMM

Click to enlarge

ComplexPrecisionDistribution

Complex HuMAP2_04697 has an average edge precision of 0.139 which is ranked 6786 out of all 6965 complexes.

Related Complexes

Genename	Complexes
CEP350	HuMAP2_01733 HuMAP2_02720 HuMAP2_03206 HuMAP2_03521 HuMAP2_04697
PCNT	HuMAP2_01666 HuMAP2_01668 HuMAP2_02965 HuMAP2_04697
PPP2R3C	HuMAP2_01733 HuMAP2_02720 HuMAP2_03206 HuMAP2_03521 HuMAP2_04697
CEP131	HuMAP2_00328 HuMAP2_00388 HuMAP2_02946 HuMAP2_04000 HuMAP2_04044 HuMAP2_04697 HuMAP2_06503
NIN	HuMAP2_01012 HuMAP2_04044 HuMAP2_04697
C2CD3	HuMAP2_04044 HuMAP2_04697 HuMAP2_06503
FAM81B	HuMAP2_01668 HuMAP2_02965 HuMAP2_04697