hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04703
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FRK | Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5) | UniProt NCBI |
| PCBP2 | Poly(rC)-binding protein 2 (Alpha-CP2) (Heterogeneous nuclear ribonucleoprotein E2) (hnRNP E2) | UniProt NCBI |
| PCBP1 | Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1) (Nucleic acid-binding protein SUB2.3) | UniProt NCBI |
| MET | Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| MIRNA:hsa-miR-4738-3p | 0.00037540551581 | 0.75 | PCBP2 PCBP1 FRK | hsa-miR-4738-3p |
| WP:WP4313 | 0.00117729775616 | 0.5 | PCBP2 PCBP1 | Ferroptosis |
| KEGG:04216 | 0.00140403658327 | 0.5 | PCBP2 PCBP1 | Ferroptosis |
| MIRNA:hsa-miR-3682-3p | 0.0126468303014 | 0.5 | PCBP2 PCBP1 | hsa-miR-3682-3p |
| CORUM:2541 | 0.0499140284799 | 0.25 | MET | HGF-Met complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FRK | PCBP1 | 1.0 | 0.949 | bioplex (PCBP1) bioplex_WMM |
| PCBP2 | PCBP1 | 0.999 | 0.948 | bioplex (PCBP1) bioplex_WMM boldt Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| PCBP1 | MET | 0.671 | 0.704 | bioplex (PCBP1) bioplex_WMM |
| FRK | MET | 0.009 | 0.097 | bioplex_WMM WMM_only |
| PCBP2 | MET | 0.007 | 0.001 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04703 has an average edge precision of 0.54 which is ranked 2273 out of all 6965 complexes.
Related Complexes