hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04716
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| LIMA1 | LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) | UniProt NCBI |
| DBN1 | Drebrin (Developmentally-regulated brain protein) | UniProt NCBI |
| GSN | Gelsolin (AGEL) (Actin-depolymerizing factor) (ADF) (Brevin) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0008064 | 0.0206993698472 | 1.0 | LIMA1 GSN DBN1 | regulation of actin polymerization or depolymerization |
| GO:0030832 | 0.0212638981157 | 1.0 | LIMA1 GSN DBN1 | regulation of actin filament length |
| GO:0008154 | 0.0406485782564 | 1.0 | LIMA1 GSN DBN1 | actin polymerization or depolymerization |
| CORUM:756 | 0.0499776345577 | 0.333333333333 | GSN | Prune-Gelsolin complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DBN1 | LIMA1 | 0.831 | 0.778 | hein_WMM bioplex_WMM youn_WMM hein (DBN1,LIMA1) gupta_WMM treiber_WMM |
| DBN1 | GSN | 0.641 | 0.688 | hein_WMM bioplex (DBN1) bioplex_WMM hein (DBN1) boldt_WMM treiber_WMM |
| LIMA1 | GSN | 0.04 | 0.268 | hein_WMM bioplex_WMM hein (LIMA1) treiber_WMM |
Images
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Complex HuMAP2_04716 has an average edge precision of 0.578 which is ranked 2041 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| LIMA1 | HuMAP2_01907 HuMAP2_02160 HuMAP2_02789 HuMAP2_04716 HuMAP2_06706 |
| DBN1 | HuMAP2_01907 HuMAP2_02160 HuMAP2_04716 HuMAP2_05657 HuMAP2_06706 |
| GSN | HuMAP2_04716 HuMAP2_05657 HuMAP2_06038 HuMAP2_06706 |