hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04726
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TYMS | Thymidylate synthase (TS) (TSase) (EC 2.1.1.45) | UniProt NCBI |
| NDRG2 | Protein NDRG2 (N-myc downstream-regulated gene 2 protein) (Protein Syld709613) | UniProt NCBI |
| HMGCS1 | Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMG-CoA synthase) (EC 2.3.3.10) (3-hydroxy-3-methylglutaryl coenzyme A synthase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00072 | 0.0333280946102 | 0.333333333333 | HMGCS1 | Synthesis and degradation of ketone bodies |
| WP:WP3963 | 0.0499785733994 | 0.333333333333 | HMGCS1 | Mevalonate pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NDRG2 | HMGCS1 | 0.114 | 0.384 | bioplex_WMM fraction |
| NDRG2 | TYMS | 0.071 | 0.353 | fraction |
| HMGCS1 | TYMS | 0.007 | 0.004 | bioplex_WMM Guru fraction |
Images
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Complex HuMAP2_04726 has an average edge precision of 0.247 which is ranked 5420 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TYMS | HuMAP2_01558 HuMAP2_04726 HuMAP2_04860 HuMAP2_06310 |
| NDRG2 | HuMAP2_00031 HuMAP2_01558 HuMAP2_04469 HuMAP2_04726 HuMAP2_06310 |
| HMGCS1 | HuMAP2_00292 HuMAP2_01959 HuMAP2_04726 HuMAP2_05645 |