hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04733
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HIF1A | Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8) | UniProt NCBI |
| KRT40 | Keratin, type I cytoskeletal 40 (Cytokeratin-40) (CK-40) (Keratin-40) (K40) (Type I hair keratin Ka36) | UniProt NCBI |
| MYH3 | Myosin-3 (Muscle embryonic myosin heavy chain) (Myosin heavy chain 3) (Myosin heavy chain, fast skeletal muscle, embryonic) (SMHCE) | UniProt NCBI |
| MYH4 | Myosin-4 (Myosin heavy chain 2b) (MyHC-2b) (Myosin heavy chain 4) (Myosin heavy chain IIb) (MyHC-IIb) (Myosin heavy chain, skeletal muscle, fetal) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04530 | 0.0206513420529 | 0.5 | MYH3 MYH4 | Tight junction |
| KEGG:05130 | 0.0307221505972 | 0.5 | MYH3 MYH4 | Pathogenic Escherichia coli infection |
| WP:WP3672 | 0.0416857670091 | 0.25 | HIF1A | LncRNA-mediated mechanisms of therapeutic resistance |
| CORUM:5382 | 0.0499140284799 | 0.25 | HIF1A | ARNT-HIF1A complex |
| CORUM:7273 | 0.0499140284799 | 0.25 | HIF1A | ARNTL-HIF1A complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HIF1A | MYH3 | 0.23 | 0.468 | bioplex (HIF1A) bioplex_WMM |
| HIF1A | MYH4 | 0.229 | 0.469 | bioplex (HIF1A) bioplex_WMM |
| MYH4 | KRT40 | 0.089 | 0.353 | bioplex () |
| KRT40 | MYH3 | 0.044 | 0.273 | bioplex () |
| MYH4 | MYH3 | 0.016 | 0.155 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04733 has an average edge precision of 0.344 which is ranked 4076 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HIF1A | HuMAP2_00710 HuMAP2_03104 HuMAP2_04482 HuMAP2_04733 HuMAP2_06061 |
| KRT40 | HuMAP2_04360 HuMAP2_04733 HuMAP2_05500 |
| MYH3 | HuMAP2_04733 HuMAP2_06061 HuMAP2_06391 |
| MYH4 | HuMAP2_02012 HuMAP2_04733 |