hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04752
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RAB22A | Ras-related protein Rab-22A (Rab-22) | UniProt NCBI |
| CHML | Rab proteins geranylgeranyltransferase component A 2 (Choroideremia-like protein) (Rab escort protein 2) (REP-2) | UniProt NCBI |
| RAB31 | Ras-related protein Rab-31 (Ras-related protein Rab-22B) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8873719 | 1.70037551742e-05 | 1.0 | CHML RAB22A RAB31 | RAB geranylgeranylation |
| KEGG:04144 | 0.0117748506163 | 0.666666666667 | RAB22A RAB31 | Endocytosis |
| MIRNA:hsa-miR-27b-5p | 0.016068864109 | 0.666666666667 | CHML RAB22A | hsa-miR-27b-5p |
| REAC:R-HSA-8876198 | 0.0238137546255 | 0.666666666667 | CHML RAB31 | RAB GEFs exchange GTP for GDP on RABs |
| REAC:R-HSA-9007101 | 0.0444303896492 | 0.666666666667 | CHML RAB31 | Rab regulation of trafficking |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RAB31 | RAB22A | 1.0 | 0.949 | bioplex (RAB31) bioplex_WMM |
| CHML | RAB31 | 0.52 | 0.633 | bioplex (RAB31) bioplex_WMM |
| CHML | RAB22A | 0.008 | 0.035 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04752 has an average edge precision of 0.539 which is ranked 2282 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RAB22A | HuMAP2_03796 HuMAP2_04471 HuMAP2_04752 HuMAP2_07002 |
| CHML | HuMAP2_01067 HuMAP2_03796 HuMAP2_04752 HuMAP2_07002 |
| RAB31 | HuMAP2_01067 HuMAP2_03796 HuMAP2_04471 HuMAP2_04752 HuMAP2_07002 |