hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04770
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MFSD4B | Sodium-dependent glucose transporter 1 (Major facilitator superfamily domain-containing protein 4B) | UniProt NCBI |
| TMEM8A | Post-GPI attachment to proteins factor 6 (EC 3.1.1.4) (GPI processing phospholipase A2) (GPI-PLA2) (Protein M83) (Transmembrane protein 6) (Transmembrane protein 8) (Transmembrane protein 8A) | UniProt NCBI |
| NOCT | Nocturnin (EC 3.1.13.4) (Carbon catabolite repression 4-like protein) (Circadian deadenylase NOC) | UniProt NCBI |
| TUBA3D | Tubulin alpha-3D chain (Alpha-tubulin 3D) [Cleaved into: Detyrosinated tubulin alpha-3D chain] | UniProt NCBI |
| FAM126A | Hyccin (Down-regulated by CTNNB1 protein A) (Protein FAM126A) | UniProt NCBI |
| ATP1A4 | Sodium/potassium-transporting ATPase subunit alpha-4 (Na(+)/K(+) ATPase alpha-4 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-4) | UniProt NCBI |
| P2RY8 | P2Y purinoceptor 8 (P2Y8) | UniProt NCBI |
| CHRM3 | Muscarinic acetylcholine receptor M3 | UniProt NCBI |
| TCP11L2 | T-complex protein 11-like protein 2 | UniProt NCBI |
| ATP1B4 | Protein ATP1B4 (X,K-ATPase subunit beta-m) (X/potassium-transporting ATPase subunit beta-m) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04971 | 0.000369500071094 | 0.3 | ATP1B4 CHRM3 ATP1A4 | Gastric acid secretion |
| KEGG:04911 | 0.000609933581564 | 0.3 | ATP1B4 CHRM3 ATP1A4 | Insulin secretion |
| KEGG:04970 | 0.000662481583065 | 0.3 | ATP1B4 CHRM3 ATP1A4 | Salivary secretion |
| KEGG:04972 | 0.000869790061312 | 0.3 | ATP1B4 CHRM3 ATP1A4 | Pancreatic secretion |
| KEGG:04964 | 0.00368246782768 | 0.2 | ATP1B4 ATP1A4 | Proximal tubule bicarbonate reclamation |
| KEGG:04960 | 0.00897691057192 | 0.2 | ATP1B4 ATP1A4 | Aldosterone-regulated sodium reabsorption |
| KEGG:04973 | 0.0150095691377 | 0.2 | ATP1B4 ATP1A4 | Carbohydrate digestion and absorption |
| KEGG:04978 | 0.0198737758517 | 0.2 | ATP1B4 ATP1A4 | Mineral absorption |
| KEGG:04961 | 0.02348841544 | 0.2 | ATP1B4 ATP1A4 | Endocrine and other factor-regulated calcium reabsorption |
| KEGG:04976 | 0.0294648827991 | 0.2 | ATP1B4 ATP1A4 | Bile secretion |
| KEGG:04918 | 0.043398064759 | 0.2 | ATP1B4 ATP1A4 | Thyroid hormone synthesis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ATP1A4 | P2RY8 | 0.959 | 0.863 | bioplex (P2RY8) bioplex_WMM |
| CHRM3 | ATP1A4 | 0.366 | 0.543 | bioplex (CHRM3) bioplex_WMM |
| ATP1B4 | ATP1A4 | 0.349 | 0.536 | bioplex (ATP1B4) bioplex_WMM |
| TUBA3D | P2RY8 | 0.306 | 0.501 | bioplex (P2RY8) bioplex_WMM |
| TUBA3D | TCP11L2 | 0.163 | 0.42 | bioplex (TUBA3D) bioplex_WMM |
| MFSD4B | TUBA3D | 0.154 | 0.414 | bioplex (TUBA3D) bioplex_WMM |
| TUBA3D | CHRM3 | 0.038 | 0.264 | bioplex (CHRM3) bioplex_WMM |
| CHRM3 | NOCT | 0.025 | 0.211 | bioplex (CHRM3) bioplex_WMM |
| FAM126A | P2RY8 | 0.023 | 0.21 | bioplex (P2RY8) bioplex_WMM |
| ATP1B4 | TMEM8A | 0.021 | 0.195 | bioplex (ATP1B4) bioplex_WMM |
| TUBA3D | ATP1A4 | 0.008 | 0.083 | bioplex_WMM WMM_only |
| ATP1A4 | TMEM8A | 0.008 | 0.068 | bioplex_WMM WMM_only |
| ATP1A4 | FAM126A | 0.008 | 0.044 | bioplex_WMM WMM_only |
| MFSD4B | TCP11L2 | 0.007 | 0.01 | bioplex_WMM WMM_only |
| TUBA3D | FAM126A | 0.007 | 0.004 | bioplex_WMM WMM_only |
| ATP1A4 | NOCT | 0.007 | 0.004 | bioplex_WMM WMM_only |
| TUBA3D | NOCT | 0.006 | 0.003 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04770 has an average edge precision of 0.257 which is ranked 5270 out of all 6965 complexes.
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