hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04783
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MYZAP | Myocardial zonula adherens protein (GRINL1A upstream protein) (Gup) | UniProt NCBI |
| POLR2G | DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19) | UniProt NCBI |
| CTDP1 | RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase) | UniProt NCBI |
| MCFD2 | Multiple coagulation factor deficiency protein 2 (Neural stem cell-derived neuronal survival protein) | UniProt NCBI |
| POLR2J2 | DNA-directed RNA polymerase II subunit RPB11-b1 (RNA polymerase II subunit B11-b1) (RPB11b1) (DNA-directed RNA polymerase II subunit J2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2685 | 0.000910544014226 | 0.4 | POLR2G CTDP1 | RNA polymerase II (RNAPII) |
| KEGG:03020 | 0.0018606832332 | 0.4 | POLR2J2 POLR2G | RNA polymerase |
| REAC:R-HSA-167242 | 0.00340529843133 | 0.4 | POLR2G CTDP1 | Abortive elongation of HIV-1 transcript in the absence of Tat |
| REAC:R-HSA-167243 | 0.00666792835349 | 0.4 | POLR2G CTDP1 | Tat-mediated HIV elongation arrest and recovery |
| REAC:R-HSA-167238 | 0.00666792835349 | 0.4 | POLR2G CTDP1 | Pausing and recovery of Tat-mediated HIV elongation |
| REAC:R-HSA-113418 | 0.00709716303977 | 0.4 | POLR2G CTDP1 | Formation of the Early Elongation Complex |
| REAC:R-HSA-167158 | 0.00709716303977 | 0.4 | POLR2G CTDP1 | Formation of the HIV-1 Early Elongation Complex |
| REAC:R-HSA-167287 | 0.0075397219523 | 0.4 | POLR2G CTDP1 | HIV elongation arrest and recovery |
| REAC:R-HSA-167290 | 0.0075397219523 | 0.4 | POLR2G CTDP1 | Pausing and recovery of HIV elongation |
| WP:WP4022 | 0.0101828011392 | 0.4 | POLR2J2 POLR2G | Pyrimidine metabolism |
| REAC:R-HSA-167200 | 0.0126969553517 | 0.4 | POLR2G CTDP1 | Formation of HIV-1 elongation complex containing HIV-1 Tat |
| REAC:R-HSA-167246 | 0.0126969553517 | 0.4 | POLR2G CTDP1 | Tat-mediated elongation of the HIV-1 transcript |
| REAC:R-HSA-167169 | 0.0126969553517 | 0.4 | POLR2G CTDP1 | HIV Transcription Elongation |
| REAC:R-HSA-167152 | 0.0138877528683 | 0.4 | POLR2G CTDP1 | Formation of HIV elongation complex in the absence of HIV Tat |
| REAC:R-HSA-112382 | 0.0229182830201 | 0.4 | POLR2G CTDP1 | Formation of RNA Pol II elongation complex |
| REAC:R-HSA-75955 | 0.0229182830201 | 0.4 | POLR2G CTDP1 | RNA Polymerase II Transcription Elongation |
| REAC:R-HSA-6796648 | 0.0253191001807 | 0.4 | POLR2G CTDP1 | TP53 Regulates Transcription of DNA Repair Genes |
| REAC:R-HSA-167172 | 0.0332320424718 | 0.4 | POLR2G CTDP1 | Transcription of the HIV genome |
| REAC:R-HSA-674695 | 0.0443461879505 | 0.4 | POLR2G CTDP1 | RNA Polymerase II Pre-transcription Events |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| POLR2G | CTDP1 | 0.166 | 0.422 | hein_WMM bioplex (POLR2G) bioplex_WMM hein (POLR2G) |
| POLR2G | MYZAP | 0.141 | 0.404 | hein_WMM hein (POLR2G) |
| POLR2G | POLR2J2 | 0.108 | 0.373 | hein_WMM hein (POLR2G) |
| POLR2G | MCFD2 | 0.08 | 0.352 | fraction |
| MYZAP | POLR2J2 | 0.008 | 0.09 | hein_WMM WMM_only |
| MYZAP | CTDP1 | 0.008 | 0.032 | hein_WMM WMM_only |
| POLR2J2 | CTDP1 | 0.007 | 0.008 | hein_WMM WMM_only |
Images
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Complex HuMAP2_04783 has an average edge precision of 0.24 which is ranked 5522 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MYZAP | HuMAP2_04783 HuMAP2_05762 HuMAP2_06266 |
| POLR2G | HuMAP2_01405 HuMAP2_02282 HuMAP2_04783 HuMAP2_05090 HuMAP2_05607 HuMAP2_05703 HuMAP2_05762 HuMAP2_05766 HuMAP2_06266 |
| CTDP1 | HuMAP2_04783 HuMAP2_05090 HuMAP2_05762 |
| MCFD2 | HuMAP2_04783 HuMAP2_05762 HuMAP2_06266 |
| POLR2J2 | HuMAP2_04783 HuMAP2_05762 HuMAP2_06266 |