hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04795
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NEK6 | Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase 6) (NimA-related protein kinase 6) (Protein kinase SID6-1512) | UniProt NCBI |
| NEK7 | Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2980767 | 3.51943927099e-05 | 1.0 | NEK6 NEK7 | Activation of NIMA Kinases NEK9, NEK6, NEK7 |
| REAC:R-HSA-3301854 | 0.000831258037338 | 1.0 | NEK6 NEK7 | Nuclear Pore Complex (NPC) Disassembly |
| REAC:R-HSA-2980766 | 0.00165916422775 | 1.0 | NEK6 NEK7 | Nuclear Envelope Breakdown |
| REAC:R-HSA-68875 | 0.0144900342557 | 1.0 | NEK6 NEK7 | Mitotic Prophase |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NEK6 | NEK7 | 1.0 | 0.949 | bioplex (NEK6) bioplex_WMM boldt boldt_WMM |
Images
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Complex HuMAP2_04795 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NEK6 | HuMAP2_00249 HuMAP2_02829 HuMAP2_03845 HuMAP2_04795 |
| NEK7 | HuMAP2_00249 HuMAP2_03845 HuMAP2_04795 |