hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04820
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) | UniProt NCBI |
| PAFAH1B3 | Platelet-activating factor acetylhydrolase IB subunit gamma (EC 3.1.1.47) (PAF acetylhydrolase 29 kDa subunit) (PAF-AH 29 kDa subunit) (PAF-AH subunit gamma) (PAFAH subunit gamma) | UniProt NCBI |
| PAFAH1B2 | Platelet-activating factor acetylhydrolase IB subunit beta (EC 3.1.1.47) (PAF acetylhydrolase 30 kDa subunit) (PAF-AH 30 kDa subunit) (PAF-AH subunit beta) (PAFAH subunit beta) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00565 | 1.79953098981e-07 | 1.0 | PAFAH1B2 PAFAH1B3 PAFAH1B1 | Ether lipid metabolism |
| REAC:R-HSA-6811436 | 8.81209945571e-06 | 1.0 | PAFAH1B2 PAFAH1B3 PAFAH1B1 | COPI-independent Golgi-to-ER retrograde traffic |
| REAC:R-HSA-8856688 | 0.000160847790881 | 1.0 | PAFAH1B2 PAFAH1B3 PAFAH1B1 | Golgi-to-ER retrograde transport |
| REAC:R-HSA-6811442 | 0.000564194667652 | 1.0 | PAFAH1B2 PAFAH1B3 PAFAH1B1 | Intra-Golgi and retrograde Golgi-to-ER traffic |
| GO:0047179 | 0.00135247023414 | 0.666666666667 | PAFAH1B2 PAFAH1B3 | platelet-activating factor acetyltransferase activity |
| KEGG:01100 | 0.0105851300972 | 1.0 | PAFAH1B2 PAFAH1B3 PAFAH1B1 | Metabolic pathways |
| REAC:R-HSA-199991 | 0.0146202486223 | 1.0 | PAFAH1B2 PAFAH1B3 PAFAH1B1 | Membrane Trafficking |
| REAC:R-HSA-5653656 | 0.0171761243356 | 1.0 | PAFAH1B2 PAFAH1B3 PAFAH1B1 | Vesicle-mediated transport |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PAFAH1B3 | PAFAH1B1 | 0.997 | 0.935 | hein_WMM bioplex (PAFAH1B3) bioplex_WMM hein (PAFAH1B1) fraction boldt_WMM |
| PAFAH1B2 | PAFAH1B3 | 0.985 | 0.899 | hein_WMM bioplex (PAFAH1B3) bioplex_WMM hein (PAFAH1B2) boldt_WMM |
| PAFAH1B2 | PAFAH1B1 | 0.876 | 0.811 | hein_WMM bioplex_WMM boldt (PAFAH1B1) hein (PAFAH1B1,PAFAH1B2) fraction boldt_WMM |
Images
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Complex HuMAP2_04820 has an average edge precision of 0.882 which is ranked 649 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PAFAH1B1 | HuMAP2_00783 HuMAP2_04820 |
| PAFAH1B3 | HuMAP2_00001 HuMAP2_02037 HuMAP2_04820 |
| PAFAH1B2 | HuMAP2_00001 HuMAP2_02037 HuMAP2_04820 |