hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04825
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ATP6V1A | V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar ATPase isoform VA68) (Vacuolar proton pump subunit alpha) | UniProt NCBI |
| MCMBP | Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein) | UniProt NCBI |
| ATP6V1H | V-type proton ATPase subunit H (V-ATPase subunit H) (Nef-binding protein 1) (NBP1) (Protein VMA13 homolog) (V-ATPase 50/57 kDa subunits) (Vacuolar proton pump subunit H) (Vacuolar proton pump subunit SFD) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05110 | 0.000504120803948 | 0.666666666667 | ATP6V1A ATP6V1H | Vibrio cholerae infection |
| KEGG:05323 | 0.00068800303931 | 0.666666666667 | ATP6V1A ATP6V1H | Rheumatoid arthritis |
| KEGG:05120 | 0.000817378611711 | 0.666666666667 | ATP6V1A ATP6V1H | Epithelial cell signaling in Helicobacter pylori infection |
| KEGG:04721 | 0.000987288198645 | 0.666666666667 | ATP6V1A ATP6V1H | Synaptic vesicle cycle |
| REAC:R-HSA-77387 | 0.00184610965854 | 0.666666666667 | ATP6V1A ATP6V1H | Insulin receptor recycling |
| REAC:R-HSA-917977 | 0.00271504560844 | 0.666666666667 | ATP6V1A ATP6V1H | Transferrin endocytosis and recycling |
| KEGG:00190 | 0.00307537091529 | 0.666666666667 | ATP6V1A ATP6V1H | Oxidative phosphorylation |
| REAC:R-HSA-1222556 | 0.0033164570092 | 0.666666666667 | ATP6V1A ATP6V1H | ROS and RNS production in phagocytes |
| KEGG:04145 | 0.00402657539006 | 0.666666666667 | ATP6V1A ATP6V1H | Phagosome |
| KEGG:04150 | 0.00458162707101 | 0.666666666667 | ATP6V1A ATP6V1H | mTOR signaling pathway |
| REAC:R-HSA-917937 | 0.00955880978777 | 0.666666666667 | ATP6V1A ATP6V1H | Iron uptake and transport |
| REAC:R-HSA-74752 | 0.011426592715 | 0.666666666667 | ATP6V1A ATP6V1H | Signaling by Insulin receptor |
| KEGG:05165 | 0.0214257750703 | 0.666666666667 | ATP6V1A ATP6V1H | Human papillomavirus infection |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ATP6V1A | ATP6V1H | 0.598 | 0.668 | hein_WMM bioplex_WMM Guru boldt youn_WMM fraction boldt_WMM |
| MCMBP | ATP6V1A | 0.108 | 0.373 | youn_WMM fraction treiber_WMM |
| MCMBP | ATP6V1H | 0.008 | 0.086 | bioplex_WMM youn_WMM fraction |
Images
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Complex HuMAP2_04825 has an average edge precision of 0.376 which is ranked 3572 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ATP6V1A | HuMAP2_00849 HuMAP2_01065 HuMAP2_01514 HuMAP2_04825 HuMAP2_05288 HuMAP2_05478 HuMAP2_06925 |
| MCMBP | HuMAP2_00191 HuMAP2_02127 HuMAP2_02938 HuMAP2_03737 HuMAP2_04825 HuMAP2_05922 |
| ATP6V1H | HuMAP2_00849 HuMAP2_04825 HuMAP2_04842 HuMAP2_05478 HuMAP2_06925 |