hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04839
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DZIP3 | E3 ubiquitin-protein ligase DZIP3 (EC 2.3.2.27) (DAZ-interacting protein 3) (RING-type E3 ubiquitin transferase DZIP3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138) | UniProt NCBI |
| GAMT | Guanidinoacetate N-methyltransferase (EC 2.1.1.2) | UniProt NCBI |
| DHFR | Dihydrofolate reductase (EC 1.5.1.3) | UniProt NCBI |
| TIA1 | Nucleolysin TIA-1 isoform p40 (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1) (p40-TIA-1) | UniProt NCBI |
| TIAL1 | Nucleolysin TIAR (TIA-1-related protein) | UniProt NCBI |
| UBL5 | Ubiquitin-like protein 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6803529 | 0.00717487015656 | 0.333333333333 | TIAL1 TIA1 | FGFR2 alternative splicing |
| REAC:R-HSA-5654738 | 0.036283735834 | 0.333333333333 | TIAL1 TIA1 | Signaling by FGFR2 |
| REAC:R-HSA-190236 | 0.0484536768126 | 0.333333333333 | TIAL1 TIA1 | Signaling by FGFR |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TIAL1 | DZIP3 | 0.37 | 0.544 | bioplex (DZIP3,TIAL1) bioplex_WMM youn_WMM treiber_WMM |
| TIA1 | DHFR | 0.355 | 0.54 | youn (TIA1) youn_WMM gupta_WMM fraction |
| TIAL1 | UBL5 | 0.318 | 0.509 | bioplex (UBL5) fraction |
| TIAL1 | DHFR | 0.217 | 0.465 | bioplex_WMM youn_WMM gupta_WMM fraction |
| TIA1 | TIAL1 | 0.188 | 0.438 | youn (TIA1) bioplex_WMM youn_WMM gupta_WMM fraction |
| GAMT | TIA1 | 0.048 | 0.294 | fraction |
| TIA1 | UBL5 | 0.011 | 0.143 | fraction |
| DZIP3 | DHFR | 0.007 | 0.007 | youn_WMM WMM_only |
| UBL5 | DHFR | 0.007 | 0.003 | youn_WMM WMM_only |
| TIA1 | DZIP3 | 0.006 | 0.001 | bioplex (DZIP3) |
| GAMT | TIAL1 | 0.004 | 0.008 | bioplex (GAMT) fraction |
| GAMT | DHFR | 0.0 | 0.012 | fraction |
| GAMT | UBL5 | 0.0 | 0.001 | fraction |
Images
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Complex HuMAP2_04839 has an average edge precision of 0.228 which is ranked 5729 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DZIP3 | HuMAP2_00009 HuMAP2_04839 |
| GAMT | HuMAP2_00009 HuMAP2_01180 HuMAP2_02116 HuMAP2_04839 HuMAP2_06862 |
| DHFR | HuMAP2_00203 HuMAP2_02674 HuMAP2_04839 HuMAP2_05594 HuMAP2_05984 |
| TIA1 | HuMAP2_00009 HuMAP2_02116 HuMAP2_04337 HuMAP2_04839 |
| TIAL1 | HuMAP2_00009 HuMAP2_00709 HuMAP2_02674 HuMAP2_04839 |
| UBL5 | HuMAP2_00009 HuMAP2_00815 HuMAP2_01965 HuMAP2_04839 |