hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04843
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IRF2BPL | Probable E3 ubiquitin-protein ligase IRF2BPL (EC 2.3.2.27) (Enhanced at puberty protein 1) (Interferon regulatory factor 2-binding protein-like) | UniProt NCBI |
| FARSB | Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS) | UniProt NCBI |
| POU2F1 | POU domain, class 2, transcription factor 1 (NF-A1) (Octamer-binding protein 1) (Oct-1) (Octamer-binding transcription factor 1) (OTF-1) | UniProt NCBI |
| ARFGAP2 | ADP-ribosylation factor GTPase-activating protein 2 (ARF GAP 2) (GTPase-activating protein ZNF289) (Zinc finger protein 289) | UniProt NCBI |
| VGLL4 | Transcription cofactor vestigial-like protein 4 (Vgl-4) | UniProt NCBI |
| IRF2BP2 | Interferon regulatory factor 2-binding protein 2 (IRF-2-binding protein 2) (IRF-2BP2) | UniProt NCBI |
| IRF2BP1 | Interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1) (IRF-2BP1) (Probable E3 ubiquitin-protein ligase IRF2BP1) (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase IRF2BP1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6848 | 3.38154272427e-09 | 0.428571428571 | IRF2BP2 IRF2BP1 IRF2BPL | IRF2BP2-IRF2BP1-IRF2BPL complex |
| HPA:032020_23 | 0.0352645679743 | 0.428571428571 | IRF2BP2 IRF2BP1 IRF2BPL | pancreas; islets of Langerhans[Approved,High] |
| CORUM:2802 | 0.0499886427319 | 0.142857142857 | POU2F1 | OCT1-SOX2 DNA-protein complex |
| CORUM:3122 | 0.0499886427319 | 0.142857142857 | POU2F1 | OCT1-OBF1-DNA complex |
| CORUM:3132 | 0.0499886427319 | 0.142857142857 | POU2F1 | OCT1-OBF1-DNA complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| IRF2BP2 | VGLL4 | 1.0 | 0.949 | bioplex (VGLL4) bioplex_WMM |
| IRF2BPL | VGLL4 | 0.996 | 0.928 | bioplex (VGLL4) bioplex_WMM |
| IRF2BP1 | VGLL4 | 0.994 | 0.923 | bioplex (IRF2BP1,VGLL4) bioplex_WMM |
| IRF2BPL | IRF2BP2 | 0.352 | 0.539 | bioplex_WMM Malo fraction |
| IRF2BP1 | IRF2BPL | 0.137 | 0.408 | bioplex (IRF2BP1) bioplex_WMM |
| ARFGAP2 | POU2F1 | 0.124 | 0.395 | fraction boldt_WMM |
| IRF2BP1 | ARFGAP2 | 0.113 | 0.382 | boldt youn_WMM fraction boldt_WMM |
| POU2F1 | FARSB | 0.106 | 0.374 | bioplex_WMM fraction |
| IRF2BP1 | IRF2BP2 | 0.091 | 0.354 | bioplex (IRF2BP1) bioplex_WMM youn_WMM |
| IRF2BP1 | FARSB | 0.067 | 0.352 | youn_WMM fraction bioplex_WMM |
| IRF2BP2 | FARSB | 0.007 | 0.003 | youn_WMM WMM_only bioplex_WMM |
| IRF2BP2 | ARFGAP2 | 0.006 | 0.004 | boldt youn_WMM gupta_WMM boldt_WMM |
| IRF2BPL | POU2F1 | 0.004 | 0.008 | fraction |
| IRF2BP1 | POU2F1 | 0.0 | 0.015 | fraction boldt_WMM |
| ARFGAP2 | FARSB | 0.0 | 0.0 | youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_04843 has an average edge precision of 0.376 which is ranked 3574 out of all 6965 complexes.
Related Complexes