hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04861
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RAC3 | Ras-related C3 botulinum toxin substrate 3 (p21-Rac3) | UniProt NCBI |
| RAC2 | Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2290 | 2.45903678934e-05 | 1.0 | RAC3 RAC2 | RalA downstream regulated genes |
| KEGG:05416 | 0.00015100395818 | 1.0 | RAC3 RAC2 | Viral myocarditis |
| WP:WP3937 | 0.000162072879297 | 1.0 | RAC3 RAC2 | Microglia Pathogen Phagocytosis Pathway |
| KEGG:04370 | 0.000216657853041 | 1.0 | RAC3 RAC2 | VEGF signaling pathway |
| KEGG:04664 | 0.000216657853041 | 1.0 | RAC3 RAC2 | Fc epsilon RI signaling pathway |
| KEGG:04662 | 0.000322579470084 | 1.0 | RAC3 RAC2 | B cell receptor signaling pathway |
| KEGG:04520 | 0.000342275638542 | 1.0 | RAC3 RAC2 | Adherens junction |
| KEGG:05212 | 0.000362555397177 | 1.0 | RAC3 RAC2 | Pancreatic cancer |
| KEGG:05210 | 0.000484525744074 | 1.0 | RAC3 RAC2 | Colorectal cancer |
| KEGG:05231 | 0.000571334782835 | 1.0 | RAC3 RAC2 | Choline metabolism in cancer |
| KEGG:04650 | 0.000707748986601 | 1.0 | RAC3 RAC2 | Natural killer cell mediated cytotoxicity |
| KEGG:04071 | 0.000858752944782 | 1.0 | RAC3 RAC2 | Sphingolipid signaling pathway |
| KEGG:05135 | 0.000906899134346 | 1.0 | RAC3 RAC2 | Yersinia infection |
| WP:WP4216 | 0.000925864609319 | 1.0 | RAC3 RAC2 | Chromosomal and microsatellite instability in colorectal cancer |
| WP:WP4298 | 0.00103391319552 | 1.0 | RAC3 RAC2 | Viral Acute Myocarditis |
| KEGG:05418 | 0.00113070596705 | 1.0 | RAC3 RAC2 | Fluid shear stress and atherosclerosis |
| KEGG:04062 | 0.00122335090758 | 1.0 | RAC3 RAC2 | Chemokine signaling pathway |
| WP:WP4263 | 0.00126789427184 | 1.0 | RAC3 RAC2 | Pancreatic adenocarcinoma pathway |
| KEGG:04310 | 0.00156562654612 | 1.0 | RAC3 RAC2 | Wnt signaling pathway |
| WP:WP185 | 0.00159390293709 | 1.0 | RAC3 RAC2 | Integrin-mediated Cell Adhesion |
| KEGG:04360 | 0.00197399377215 | 1.0 | RAC3 RAC2 | Axon guidance |
| WP:WP710 | 0.00199554561268 | 1.0 | RAC3 RAC2 | DNA Damage Response (only ATM dependent) |
| KEGG:04024 | 0.00209581822151 | 1.0 | RAC3 RAC2 | cAMP signaling pathway |
| KEGG:04015 | 0.00217066366165 | 1.0 | RAC3 RAC2 | Rap1 signaling pathway |
| KEGG:04014 | 0.00245633105307 | 1.0 | RAC3 RAC2 | Ras signaling pathway |
| KEGG:04810 | 0.00253730419006 | 1.0 | RAC3 RAC2 | Regulation of actin cytoskeleton |
| KEGG:04510 | 0.00259201576911 | 1.0 | RAC3 RAC2 | Focal adhesion |
| KEGG:05170 | 0.00287432751701 | 1.0 | RAC3 RAC2 | Human immunodeficiency virus 1 infection |
| KEGG:05163 | 0.0029618660435 | 1.0 | RAC3 RAC2 | Human cytomegalovirus infection |
| WP:WP51 | 0.00322133819403 | 1.0 | RAC3 RAC2 | Regulation of Actin Cytoskeleton |
| WP:WP4223 | 0.00444675819405 | 1.0 | RAC3 RAC2 | Ras Signaling |
| KEGG:04010 | 0.00476209584058 | 1.0 | RAC3 RAC2 | MAPK signaling pathway |
| WP:WP306 | 0.00654923464894 | 1.0 | RAC3 RAC2 | Focal Adhesion |
| REAC:R-HSA-4086400 | 0.00686290657842 | 1.0 | RAC3 RAC2 | PCP/CE pathway |
| WP:WP382 | 0.00889388896944 | 1.0 | RAC3 RAC2 | MAPK Signaling Pathway |
| REAC:R-HSA-194840 | 0.0142704882821 | 1.0 | RAC3 RAC2 | Rho GTPase cycle |
| REAC:R-HSA-3858494 | 0.0156129029755 | 1.0 | RAC3 RAC2 | Beta-catenin independent WNT signaling |
| KEGG:05200 | 0.0157394270613 | 1.0 | RAC3 RAC2 | Pathways in cancer |
| WP:WP4146 | 0.038834152205 | 0.5 | RAC2 | Macrophage markers |
| HP:0012618 | 0.0497341708567 | 0.5 | RAC2 | Urachal cyst |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RAC3 | RAC2 | 0.94 | 0.852 | bioplex (RAC2) bioplex_WMM |
Images
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Complex HuMAP2_04861 has an average edge precision of 0.852 which is ranked 756 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RAC3 | HuMAP2_00873 HuMAP2_04052 HuMAP2_04080 HuMAP2_04861 HuMAP2_06986 |
| RAC2 | HuMAP2_00873 HuMAP2_04052 HuMAP2_04080 HuMAP2_04861 HuMAP2_06986 |