hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04873
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| BABAM1 | BRISC and BRCA1-A complex member 1 (Mediator of RAP80 interactions and targeting subunit of 40 kDa) (New component of the BRCA1-A complex) | UniProt NCBI |
| BABAM2 | BRISC and BRCA1-A complex member 2 (BRCA1-A complex subunit BRE) (BRCA1/BRCA2-containing complex subunit 45) (Brain and reproductive organ-expressed protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03440 | 0.000113800084426 | 1.0 | BABAM2 BABAM1 | Homologous recombination |
| REAC:R-HSA-5689901 | 0.00111616502594 | 1.0 | BABAM2 BABAM1 | Metalloprotease DUBs |
| REAC:R-HSA-5693571 | 0.00393171644273 | 1.0 | BABAM2 BABAM1 | Nonhomologous End-Joining (NHEJ) |
| GO:0070552 | 0.00450823411379 | 1.0 | BABAM2 BABAM1 | BRISC complex |
| REAC:R-HSA-5693565 | 0.00477638186777 | 1.0 | BABAM2 BABAM1 | Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks |
| REAC:R-HSA-5693606 | 0.00490375205091 | 1.0 | BABAM2 BABAM1 | DNA Double Strand Break Response |
| REAC:R-HSA-69473 | 0.00732546145404 | 1.0 | BABAM2 BABAM1 | G2/M DNA damage checkpoint |
| REAC:R-HSA-5693607 | 0.00780309964082 | 1.0 | BABAM2 BABAM1 | Processing of DNA double-strand break ends |
| GO:0070531 | 0.00946729163895 | 1.0 | BABAM2 BABAM1 | BRCA1-A complex |
| REAC:R-HSA-5693567 | 0.014052618232 | 1.0 | BABAM2 BABAM1 | HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) |
| REAC:R-HSA-5693538 | 0.0153849773846 | 1.0 | BABAM2 BABAM1 | Homology Directed Repair |
| REAC:R-HSA-5693532 | 0.0224003929981 | 1.0 | BABAM2 BABAM1 | DNA Double-Strand Break Repair |
| REAC:R-HSA-69481 | 0.023229975112 | 1.0 | BABAM2 BABAM1 | G2/M Checkpoints |
| GO:0072425 | 0.0351642260875 | 1.0 | BABAM2 BABAM1 | signal transduction involved in G2 DNA damage checkpoint |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| BABAM1 | BABAM2 | 1.0 | 0.949 | hein_WMM bioplex (BABAM1) bioplex_WMM boldt youn_WMM Malo fraction boldt_WMM |
Images
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Complex HuMAP2_04873 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| BABAM1 | HuMAP2_02106 HuMAP2_03499 HuMAP2_04873 HuMAP2_04891 |
| BABAM2 | HuMAP2_03499 HuMAP2_04873 HuMAP2_04891 |