hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_04886

Confidence: Medium

Genename	Protein Name	Links
TNFSF13B	Tumor necrosis factor ligand superfamily member 13B (B lymphocyte stimulator) (BLyS) (B-cell-activating factor) (BAFF) (Dendritic cell-derived TNF-like molecule) (TNF- and APOL-related leukocyte expressed ligand 1) (TALL-1) (CD antigen CD257) [Cleaved into: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form]	UniProt NCBI
MAP3K6	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 2)	UniProt NCBI
MAP3K5	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)	UniProt NCBI
TMEM131	Transmembrane protein 131 (Protein RW1)	UniProt NCBI
FAM160B2	Protein FAM160B2 (Retinoic acid-induced protein 16)	UniProt NCBI
PDSS1	Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.91) (All-trans-decaprenyl-diphosphate synthase subunit 1) (Decaprenyl pyrophosphate synthase subunit 1) (Trans-prenyltransferase 1) (TPT 1)	UniProt NCBI
FAM160B1	Protein FAM160B1	UniProt NCBI
MAP3K15	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15)	UniProt NCBI
CYBA	Cytochrome b-245 light chain (Cytochrome b(558) alpha chain) (Cytochrome b558 subunit alpha) (Neutrophil cytochrome b 22 kDa polypeptide) (Superoxide-generating NADPH oxidase light chain subunit) (p22 phagocyte B-cytochrome) (p22-phox) (p22phox)	UniProt NCBI
TTC17	Tetratricopeptide repeat protein 17 (TPR repeat protein 17)	UniProt NCBI
HOOK2	Protein Hook homolog 2 (h-hook2) (hHK2)	UniProt NCBI
MFAP3	Microfibril-associated glycoprotein 3	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0004709	0.0226023794314	0.25	MAP3K6 MAP3K15 MAP3K5	MAP kinase kinase kinase activity
CORUM:5691	0.0499809905632	0.0833333333333	TNFSF13B	TALL1 homo-oligomer complex

Edges

Protein 1	Protein 2	Score	Precision	Evidence
MAP3K15	TNFSF13B	0.984	0.899	bioplex (TNFSF13B) bioplex_WMM
FAM160B1	TNFSF13B	0.974	0.886	bioplex (TNFSF13B) bioplex_WMM
HOOK2	TNFSF13B	0.817	0.773	bioplex (TNFSF13B) bioplex_WMM
TNFSF13B	MAP3K5	0.791	0.758	bioplex (TNFSF13B) bioplex_WMM
MAP3K6	TNFSF13B	0.397	0.557	bioplex (TNFSF13B) bioplex_WMM
PDSS1	TNFSF13B	0.161	0.416	bioplex (TNFSF13B) bioplex_WMM
TNFSF13B	FAM160B2	0.155	0.416	bioplex (TNFSF13B) bioplex_WMM
TNFSF13B	MFAP3	0.062	0.344	bioplex (TNFSF13B) bioplex_WMM
TNFSF13B	TTC17	0.048	0.294	bioplex (TNFSF13B) bioplex_WMM
TNFSF13B	CYBA	0.026	0.215	bioplex (TNFSF13B) bioplex_WMM
TNFSF13B	TMEM131	0.025	0.211	bioplex (TNFSF13B) bioplex_WMM
TMEM131	TTC17	0.017	0.175	bioplex_WMM youn_WMM WMM_only
FAM160B1	HOOK2	0.011	0.143	bioplex_WMM WMM_only
MAP3K15	MAP3K5	0.009	0.104	bioplex_WMM WMM_only
MAP3K6	MAP3K5	0.009	0.108	bioplex_WMM WMM_only
FAM160B1	MAP3K5	0.009	0.101	bioplex_WMM WMM_only
MAP3K6	MAP3K15	0.009	0.095	bioplex_WMM WMM_only
PDSS1	MAP3K5	0.009	0.099	bioplex_WMM WMM_only
MAP3K15	FAM160B1	0.009	0.099	bioplex_WMM WMM_only
MAP3K5	FAM160B2	0.008	0.091	bioplex_WMM WMM_only
PDSS1	MAP3K15	0.008	0.089	bioplex_WMM WMM_only
HOOK2	MAP3K5	0.008	0.089	bioplex_WMM WMM_only
MAP3K6	FAM160B1	0.008	0.085	bioplex_WMM WMM_only
MAP3K15	FAM160B2	0.008	0.085	bioplex_WMM WMM_only
MAP3K15	HOOK2	0.008	0.077	bioplex_WMM WMM_only
PDSS1	MAP3K6	0.008	0.074	bioplex_WMM WMM_only
MAP3K6	FAM160B2	0.008	0.067	bioplex_WMM WMM_only
PDSS1	FAM160B1	0.008	0.066	bioplex_WMM WMM_only
FAM160B1	FAM160B2	0.008	0.06	bioplex_WMM WMM_only
MAP3K6	HOOK2	0.008	0.044	bioplex_WMM WMM_only
HOOK2	FAM160B2	0.008	0.041	bioplex_WMM WMM_only
PDSS1	FAM160B2	0.008	0.034	bioplex_WMM WMM_only
MAP3K5	MFAP3	0.008	0.028	bioplex_WMM WMM_only
MAP3K5	CYBA	0.008	0.013	bioplex_WMM WMM_only
PDSS1	HOOK2	0.008	0.012	bioplex_WMM WMM_only
MAP3K5	TMEM131	0.007	0.011	bioplex_WMM WMM_only
MAP3K15	MFAP3	0.007	0.006	bioplex_WMM WMM_only
MAP3K5	TTC17	0.007	0.006	bioplex_WMM WMM_only
MAP3K15	CYBA	0.007	0.006	bioplex_WMM WMM_only
MAP3K15	TMEM131	0.007	0.007	bioplex_WMM WMM_only
FAM160B2	MFAP3	0.007	0.007	bioplex_WMM WMM_only
MAP3K15	TTC17	0.007	0.006	bioplex_WMM WMM_only
MAP3K6	MFAP3	0.007	0.004	bioplex_WMM WMM_only
TMEM131	FAM160B2	0.007	0.005	bioplex_WMM WMM_only
MAP3K6	CYBA	0.007	0.002	bioplex_WMM WMM_only
FAM160B1	MFAP3	0.007	0.001	bioplex_WMM WMM_only
FAM160B2	TTC17	0.007	0.002	bioplex_WMM WMM_only
FAM160B1	CYBA	0.007	0.001	bioplex_WMM youn_WMM WMM_only
PDSS1	MFAP3	0.007	0.004	bioplex_WMM WMM_only
MAP3K6	TMEM131	0.007	0.002	bioplex_WMM WMM_only
FAM160B2	CYBA	0.007	0.002	bioplex_WMM WMM_only
MAP3K6	TTC17	0.007	0.001	bioplex_WMM WMM_only
FAM160B1	TMEM131	0.007	0.005	bioplex_WMM WMM_only
FAM160B1	TTC17	0.007	0.004	bioplex_WMM WMM_only
PDSS1	CYBA	0.007	0.004	bioplex_WMM WMM_only
HOOK2	MFAP3	0.007	0.003	bioplex_WMM WMM_only
PDSS1	TMEM131	0.007	0.002	bioplex_WMM WMM_only
PDSS1	TTC17	0.007	0.002	bioplex_WMM WMM_only
HOOK2	CYBA	0.007	0.002	bioplex_WMM WMM_only
HOOK2	TMEM131	0.007	0.005	bioplex_WMM WMM_only
HOOK2	TTC17	0.006	0.005	bioplex_WMM WMM_only
TMEM131	CYBA	0.005	0.01	bioplex_WMM WMM_only
TMEM131	MFAP3	0.005	0.01	bioplex_WMM WMM_only
TTC17	MFAP3	0.005	0.007	bioplex_WMM WMM_only
CYBA	MFAP3	0.005	0.011	bioplex_WMM WMM_only
CYBA	TTC17	0.004	0.012	bioplex_WMM WMM_only

Images

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Complex HuMAP2_04886 has an average edge precision of 0.118 which is ranked 6880 out of all 6965 complexes.

Related Complexes

Genename	Complexes
TNFSF13B	HuMAP2_03773 HuMAP2_04886
MAP3K6	HuMAP2_01123 HuMAP2_02165 HuMAP2_04886 HuMAP2_06243 HuMAP2_06834
MAP3K5	HuMAP2_03773 HuMAP2_04886
TMEM131	HuMAP2_04886
FAM160B2	HuMAP2_04886
PDSS1	HuMAP2_00106 HuMAP2_00306 HuMAP2_04886
FAM160B1	HuMAP2_02675 HuMAP2_03773 HuMAP2_04886
MAP3K15	HuMAP2_02307 HuMAP2_03773 HuMAP2_04886
CYBA	HuMAP2_04886
TTC17	HuMAP2_04886
HOOK2	HuMAP2_03373 HuMAP2_03773 HuMAP2_03893 HuMAP2_04886 HuMAP2_05370
MFAP3	HuMAP2_04886

hu.MAP 2.0: Complex View

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Complex: HuMAP2_04886