hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_04889
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| BRINP3 | BMP/retinoic acid-inducible neural-specific protein 3 (DBCCR1-like protein 1) | UniProt NCBI |
| STIM2 | Stromal interaction molecule 2 | UniProt NCBI |
| STIM1 | Stromal interaction molecule 1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0032237 | 0.00405722906526 | 0.666666666667 | STIM2 STIM1 | activation of store-operated calcium channel activity |
| KEGG:04020 | 0.00558575423654 | 0.666666666667 | STIM2 STIM1 | Calcium signaling pathway |
| GO:1901341 | 0.00811409485621 | 0.666666666667 | STIM2 STIM1 | positive regulation of store-operated calcium channel activity |
| GO:1901339 | 0.0135228859698 | 0.666666666667 | STIM2 STIM1 | regulation of store-operated calcium channel activity |
| CORUM:6108 | 0.0249904952816 | 0.333333333333 | STIM1 | STIM1-TRPV4 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| STIM1 | STIM2 | 0.658 | 0.696 | bioplex (STIM2) bioplex_WMM youn_WMM gupta_WMM boldt_WMM |
| BRINP3 | STIM2 | 0.062 | 0.342 | bioplex (STIM2) bioplex_WMM |
| STIM1 | BRINP3 | 0.008 | 0.028 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04889 has an average edge precision of 0.355 which is ranked 3840 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| BRINP3 | HuMAP2_01244 HuMAP2_04889 |
| STIM2 | HuMAP2_01244 HuMAP2_01321 HuMAP2_01616 HuMAP2_04889 |
| STIM1 | HuMAP2_00127 HuMAP2_01616 HuMAP2_02179 HuMAP2_02898 HuMAP2_04889 |