hu.MAP 2.0: Complex View

Human Protein Complex Map

Genename	Protein Name	Links
GFPT1	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 1) (Glutamine:fructose-6-phosphate amidotransferase 1) (GFAT 1) (GFAT1) (Hexosephosphate aminotransferase 1)	UniProt NCBI
ORC4	Origin recognition complex subunit 4	UniProt NCBI
SIRT6	NAD-dependent protein deacetylase sirtuin-6 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 6) (SIR2-like protein 6)	UniProt NCBI
IL17RA	Interleukin-17 receptor A (IL-17 receptor A) (IL-17RA) (CDw217) (CD antigen CD217)	UniProt NCBI
NR3C1	Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)	UniProt NCBI
ZNF318	Zinc finger protein 318 (Endocrine regulatory protein)	UniProt NCBI
ACADM	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.8.7)	UniProt NCBI
GFPT2	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 2) (Glutamine:fructose-6-phosphate amidotransferase 2) (GFAT 2) (GFAT2) (Hexosephosphate aminotransferase 2)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-446210	0.00125133439335	0.25	GFPT1 GFPT2	Synthesis of UDP-N-acetyl-glucosamine
KEGG:00250	0.00635546714027	0.25	GFPT1 GFPT2	Alanine, aspartate and glutamate metabolism
KEGG:00520	0.0124147017773	0.25	GFPT1 GFPT2	Amino sugar and nucleotide sugar metabolism
GO:0004360	0.0126230555186	0.25	GFPT1 GFPT2	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO:0070548	0.0126230555186	0.25	GFPT1 GFPT2	L-glutamine aminotransferase activity
CORUM:4216	0.0497224828424	0.125	NR3C1	HNRNPU-NR3C1 complex

Protein 1	Protein 2	Score	Precision	Evidence
GFPT1	GFPT2	0.361	0.544	bioplex (GFPT2) bioplex_WMM treiber_WMM
SIRT6	GFPT2	0.296	0.496	bioplex () bioplex_WMM
GFPT1	SIRT6	0.075	0.357	bioplex (SIRT6) bioplex_WMM
NR3C1	IL17RA	0.065	0.347	bioplex (IL17RA) bioplex_WMM
NR3C1	SIRT6	0.063	0.348	bioplex (SIRT6) bioplex_WMM
GFPT2	ACADM	0.039	0.264	bioplex (GFPT2) bioplex_WMM Guru fraction
SIRT6	ZNF318	0.028	0.233	bioplex (SIRT6) bioplex_WMM
GFPT1	ACADM	0.026	0.224	bioplex_WMM Guru fraction treiber_WMM
ACADM	ORC4	0.025	0.218	bioplex_WMM fraction
NR3C1	ZNF318	0.009	0.09	bioplex_WMM youn_WMM gupta_WMM WMM_only
IL17RA	ZNF318	0.008	0.066	bioplex (IL17RA) bioplex_WMM
GFPT1	ORC4	0.007	0.003	bioplex_WMM youn_WMM gupta_WMM WMM_only
ORC4	ZNF318	0.007	0.005	youn_WMM gupta_WMM WMM_only
GFPT1	NR3C1	0.007	0.004	youn_WMM WMM_only
GFPT1	ZNF318	0.007	0.002	youn_WMM gupta_WMM WMM_only
NR3C1	ORC4	0.007	0.0	youn_WMM gupta_WMM WMM_only
ACADM	ZNF318	0.007	0.002	bioplex_WMM WMM_only
GFPT2	ORC4	0.007	0.001	bioplex_WMM WMM_only
SIRT6	ORC4	0.007	0.001	bioplex_WMM WMM_only
IL17RA	SIRT6	0.007	0.002	bioplex_WMM WMM_only
IL17RA	GFPT2	0.007	0.004	bioplex_WMM WMM_only
IL17RA	ACADM	0.007	0.004	bioplex (IL17RA) bioplex_WMM
SIRT6	ACADM	0.007	0.002	bioplex (SIRT6)
IL17RA	ORC4	0.005	0.007	bioplex (IL17RA) bioplex_WMM
GFPT1	IL17RA	0.004	0.016	bioplex (IL17RA) bioplex_WMM

Click to enlarge

Complex HuMAP2_04924 has an average edge precision of 0.13 which is ranked 6829 out of all 6965 complexes.

Genename	Complexes
GFPT1	HuMAP2_00192 HuMAP2_03921 HuMAP2_04025 HuMAP2_04924 HuMAP2_06529
ORC4	HuMAP2_04444 HuMAP2_04533 HuMAP2_04924
SIRT6	HuMAP2_00192 HuMAP2_03921 HuMAP2_04025 HuMAP2_04924 HuMAP2_06529
IL17RA	HuMAP2_00192 HuMAP2_00500 HuMAP2_04924
NR3C1	HuMAP2_00192 HuMAP2_00500 HuMAP2_04025 HuMAP2_04924
ZNF318	HuMAP2_04924 HuMAP2_06529
ACADM	HuMAP2_02895 HuMAP2_04444 HuMAP2_04924 HuMAP2_06529
GFPT2	HuMAP2_00192 HuMAP2_03921 HuMAP2_04025 HuMAP2_04924 HuMAP2_06529