hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04928
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ANXA7 | Annexin A7 (Annexin VII) (Annexin-7) (Synexin) | UniProt NCBI |
| ANXA11 | Annexin A11 (56 kDa autoantigen) (Annexin XI) (Annexin-11) (Calcyclin-associated annexin 50) (CAP-50) | UniProt NCBI |
| CFL2 | Cofilin-2 (Cofilin, muscle isoform) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0030196 | 0.0112458624499 | 0.666666666667 | ANXA11 CFL2 | Fatigable weakness of respiratory muscles |
| HP:0003473 | 0.0376620740847 | 0.666666666667 | ANXA11 CFL2 | Fatigable weakness |
| HP:0003398 | 0.0384790851177 | 0.666666666667 | ANXA11 CFL2 | Abnormal synaptic transmission at the neuromuscular junction |
| HP:0012535 | 0.0384790851177 | 0.666666666667 | ANXA11 CFL2 | Abnormal synaptic transmission |
| HP:0030191 | 0.0384790851177 | 0.666666666667 | ANXA11 CFL2 | Abnormal peripheral nervous system synaptic transmission |
| CORUM:6365 | 0.0499776345577 | 0.333333333333 | ANXA7 | Synexin-sorcin complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ANXA11 | ANXA7 | 0.71 | 0.729 | bioplex (ANXA11) fraction treiber_WMM |
| CFL2 | ANXA7 | 0.573 | 0.655 | bioplex (ANXA7) bioplex_WMM youn_WMM fraction |
| ANXA11 | CFL2 | 0.0 | 0.008 | bioplex (ANXA11) bioplex_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_04928 has an average edge precision of 0.464 which is ranked 2777 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ANXA7 | HuMAP2_02184 HuMAP2_02296 HuMAP2_03103 HuMAP2_04928 |
| ANXA11 | HuMAP2_01249 HuMAP2_02184 HuMAP2_03103 HuMAP2_04928 HuMAP2_06342 |
| CFL2 | HuMAP2_01910 HuMAP2_02296 HuMAP2_03344 HuMAP2_04928 HuMAP2_06767 |