hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04935
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| OTUB1 | Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (hOTU1) (Ubiquitin-specific-processing protease OTUB1) | UniProt NCBI |
| POFUT2 | GDP-fucose protein O-fucosyltransferase 2 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 2) (O-FucT-2) | UniProt NCBI |
| SIDT2 | SID1 transmembrane family member 2 | UniProt NCBI |
| TMA7 | Translation machinery-associated protein 7 (Coiled-coil domain-containing protein 72) | UniProt NCBI |
| OTUD6B | Deubiquitinase OTUD6B (EC 3.4.19.12) (DUBA-5) (OTU domain-containing protein 6B) | UniProt NCBI |
| PTH1R | Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor) | UniProt NCBI |
| MCTS1 | Malignant T-cell-amplified sequence 1 (MCT-1) (Multiple copies T-cell malignancies) | UniProt NCBI |
| C1QL4 | Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) | UniProt NCBI |
| COL10A1 | Collagen alpha-1(X) chain | UniProt NCBI |
| DUS3L | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like (EC 1.3.1.-) (tRNA-dihydrouridine synthase 3-like) | UniProt NCBI |
| DNAJC17 | DnaJ homolog subfamily C member 17 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0005871 | 0.0199824075146 | 0.181818181818 | COL10A1 PTH1R | Metaphyseal chondrodysplasia |
| HP:0003021 | 0.0330218557658 | 0.181818181818 | COL10A1 PTH1R | Metaphyseal cupping |
| WP:WP474 | 0.0419429821725 | 0.181818181818 | COL10A1 PTH1R | Endochondral Ossification |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MCTS1 | OTUD6B | 0.998 | 0.944 | fraction |
| DNAJC17 | OTUD6B | 0.905 | 0.828 | fraction |
| DNAJC17 | DUS3L | 0.831 | 0.778 | fraction |
| OTUD6B | DUS3L | 0.384 | 0.55 | fraction |
| DUS3L | C1QL4 | 0.365 | 0.544 | bioplex (C1QL4) bioplex_WMM |
| DNAJC17 | MCTS1 | 0.237 | 0.47 | fraction |
| DNAJC17 | PTH1R | 0.112 | 0.381 | bioplex (PTH1R) bioplex_WMM |
| SIDT2 | PTH1R | 0.044 | 0.275 | bioplex (PTH1R) bioplex_WMM |
| OTUD6B | OTUB1 | 0.041 | 0.271 | fraction |
| POFUT2 | MCTS1 | 0.038 | 0.261 | fraction |
| C1QL4 | COL10A1 | 0.031 | 0.238 | bioplex (COL10A1) bioplex_WMM |
| MCTS1 | OTUB1 | 0.03 | 0.24 | bioplex_WMM gupta_WMM fraction treiber_WMM |
| DUS3L | TMA7 | 0.022 | 0.205 | fraction |
| MCTS1 | TMA7 | 0.015 | 0.14 | bioplex_WMM fraction |
| DNAJC17 | SIDT2 | 0.008 | 0.07 | bioplex_WMM WMM_only |
| DNAJC17 | TMA7 | 0.007 | 0.004 | fraction |
| SIDT2 | C1QL4 | 0.007 | 0.0 | bioplex_WMM WMM_only |
| POFUT2 | OTUB1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| POFUT2 | TMA7 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| POFUT2 | C1QL4 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| SIDT2 | TMA7 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| OTUB1 | TMA7 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| OTUD6B | TMA7 | 0.006 | 0.009 | fraction |
| POFUT2 | COL10A1 | 0.005 | 0.012 | bioplex (COL10A1) bioplex_WMM |
| OTUB1 | DUS3L | 0.005 | 0.007 | fraction |
| DNAJC17 | OTUB1 | 0.005 | 0.008 | youn_WMM fraction |
| MCTS1 | DUS3L | 0.0 | 0.009 | fraction |
| POFUT2 | DUS3L | 0.0 | 0.007 | fraction |
Images
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Complex HuMAP2_04935 has an average edge precision of 0.224 which is ranked 5799 out of all 6965 complexes.
Related Complexes