hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04980
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SEMA4B | Semaphorin-4B (Semaphorin-C) | UniProt NCBI |
| ASAH1 | Acid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylethanolamine hydrolase ASAH1) (EC 3.5.1.-) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta] | UniProt NCBI |
| AEN | Apoptosis-enhancing nuclease (EC 3.1.-.-) (Interferon-stimulated 20 kDa exonuclease-like 1) | UniProt NCBI |
| INPP5K | Inositol polyphosphate 5-phosphatase K (EC 3.1.3.56) (Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase) (EC 3.1.3.86) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (EC 3.1.3.36) (Skeletal muscle and kidney-enriched inositol phosphatase) | UniProt NCBI |
| ACE2 | Angiotensin-converting enzyme 2 (EC 3.4.17.23) (ACE-related carboxypeptidase) (Angiotensin-converting enzyme homolog) (ACEH) (Metalloprotease MPROT15) [Cleaved into: Processed angiotensin-converting enzyme 2] | UniProt NCBI |
| AAMP | Angio-associated migratory cell protein | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7098 | 0.0499726005494 | 0.166666666667 | ASAH1 | ASAH1-NR5A1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| AAMP | AEN | 0.26 | 0.482 | bioplex (AAMP) bioplex_WMM |
| AAMP | ASAH1 | 0.177 | 0.436 | bioplex (AAMP) bioplex_WMM |
| AAMP | ACE2 | 0.086 | 0.351 | bioplex (AAMP) bioplex_WMM |
| AAMP | INPP5K | 0.032 | 0.242 | bioplex (AAMP,INPP5K) bioplex_WMM |
| AEN | SEMA4B | 0.027 | 0.225 | bioplex (AEN) bioplex_WMM |
| ACE2 | AEN | 0.009 | 0.108 | bioplex_WMM WMM_only |
| ACE2 | ASAH1 | 0.008 | 0.041 | bioplex_WMM WMM_only |
| ACE2 | INPP5K | 0.008 | 0.028 | bioplex_WMM WMM_only |
| AEN | ASAH1 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| AEN | INPP5K | 0.007 | 0.004 | bioplex_WMM WMM_only |
| ASAH1 | INPP5K | 0.006 | 0.006 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04980 has an average edge precision of 0.176 which is ranked 6469 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SEMA4B | HuMAP2_02679 HuMAP2_04980 |
| ASAH1 | HuMAP2_00834 HuMAP2_00989 HuMAP2_01734 HuMAP2_03338 HuMAP2_04980 HuMAP2_06143 |
| AEN | HuMAP2_00834 HuMAP2_01734 HuMAP2_02679 HuMAP2_04980 |
| INPP5K | HuMAP2_01734 HuMAP2_04980 |
| ACE2 | HuMAP2_00834 HuMAP2_01734 HuMAP2_04980 |
| AAMP | HuMAP2_00215 HuMAP2_00834 HuMAP2_01734 HuMAP2_04712 HuMAP2_04980 |