hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_04981
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CD3EAP | DNA-directed RNA polymerase I subunit RPA34 (A34.5) (Antisense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CAST) (CD3E-associated protein) (RNA polymerase I-associated factor PAF49) | UniProt NCBI |
| POLR1E | DNA-directed RNA polymerase I subunit RPA49 (RNA polymerase I subunit A49) (DNA-directed RNA polymerase I subunit E) (RNA polymerase I-associated factor 1) (RNA polymerase I-associated factor 53) | UniProt NCBI |
| ZNRD1 | DNA-directed RNA polymerase I subunit RPA12 (Zinc ribbon domain-containing protein 1) | UniProt NCBI |
| POLR1A | DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-73863 | 2.85355515963e-09 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | RNA Polymerase I Transcription Termination |
| REAC:R-HSA-73762 | 1.61758895931e-08 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | RNA Polymerase I Transcription Initiation |
| GO:0001054 | 1.74428263667e-08 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | RNA polymerase I activity |
| GO:0005736 | 1.74428263667e-08 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | RNA polymerase I complex |
| REAC:R-HSA-5250924 | 2.21430620378e-07 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | B-WICH complex positively regulates rRNA expression |
| REAC:R-HSA-73772 | 2.31729719e-07 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | RNA Polymerase I Promoter Escape |
| REAC:R-HSA-5250913 | 4.1700321538e-07 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | Positive epigenetic regulation of rRNA expression |
| REAC:R-HSA-427413 | 4.33518194207e-07 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | NoRC negatively regulates rRNA expression |
| REAC:R-HSA-5250941 | 4.8601535637e-07 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | Negative epigenetic regulation of rRNA expression |
| REAC:R-HSA-73854 | 5.04530227089e-07 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | RNA Polymerase I Promoter Clearance |
| REAC:R-HSA-73864 | 5.23569103583e-07 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | RNA Polymerase I Transcription |
| GO:0006362 | 5.79418977671e-07 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | transcription elongation from RNA polymerase I promoter |
| GO:0006363 | 7.6760633794e-07 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | termination of RNA polymerase I transcription |
| GO:0006361 | 8.77264386218e-07 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | transcription initiation from RNA polymerase I promoter |
| KEGG:03020 | 1.09102814336e-06 | 0.75 | POLR1A POLR1E ZNRD1 | RNA polymerase |
| CORUM:5233 | 1.36522213713e-06 | 0.75 | POLR1A POLR1E CD3EAP | TNF-alpha/NF-kappa B signaling complex 5 |
| GO:0003899 | 1.61120484949e-06 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | DNA-directed 5'-3' RNA polymerase activity |
| REAC:R-HSA-212165 | 1.64727717851e-06 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | Epigenetic regulation of gene expression |
| GO:0034062 | 2.22951035196e-06 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | 5'-3' RNA polymerase activity |
| GO:0097747 | 2.22951035196e-06 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | RNA polymerase activity |
| GO:0006360 | 1.11030542559e-05 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | transcription by RNA polymerase I |
| GO:0045815 | 1.11030542559e-05 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | positive regulation of gene expression, epigenetic |
| WP:WP4022 | 1.77747861039e-05 | 0.75 | POLR1A POLR1E ZNRD1 | Pyrimidine metabolism |
| GO:0006353 | 2.65528608423e-05 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | DNA-templated transcription, termination |
| GO:0055029 | 8.10410789889e-05 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | nuclear DNA-directed RNA polymerase complex |
| GO:0000428 | 8.45267167948e-05 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | DNA-directed RNA polymerase complex |
| GO:0030880 | 9.56604850625e-05 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | RNA polymerase complex |
| GO:0006354 | 0.000116616394242 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | DNA-templated transcription, elongation |
| GO:0016779 | 0.000146105138915 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | nucleotidyltransferase activity |
| HPA:041010_12 | 0.000470883984016 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | skeletal muscle; myocytes[Supported,Medium] |
| HPA:006020_12 | 0.000505173188526 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | caudate; neuronal cells[Supported,Medium] |
| HPA:009020_12 | 0.000593649509043 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cervix, uterine; squamous epithelial cells[Supported,Medium] |
| HPA:014010_11 | 0.000611914370533 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | endometrium 2; cells in endometrial stroma[Supported,Low] |
| HPA:011030_11 | 0.000677181505515 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | colon; peripheral nerve/ganglion[Supported,Low] |
| HPA:007010_12 | 0.000689220025944 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cerebellum; Purkinje cells[Supported,Medium] |
| HPA:009010_12 | 0.000701418347439 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cervix, uterine; glandular cells[Supported,Medium] |
| GO:0044452 | 0.000744257224193 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | nucleolar part |
| HPA:058010_12 | 0.000800399578421 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | vagina; squamous epithelial cells[Supported,Medium] |
| HPA:031020_11 | 0.000870365491093 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | ovary; ovarian stroma cells[Supported,Low] |
| HPA:050020_11 | 0.00094994907404 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | spleen; cells in white pulp[Supported,Low] |
| HPA:056030_12 | 0.000965458161917 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | tonsil; squamous epithelial cells[Supported,Medium] |
| HPA:014020_12 | 0.000965458161917 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | endometrium 2; glandular cells[Supported,Medium] |
| HPA:030010_12 | 0.000975902533272 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | oral mucosa; squamous epithelial cells[Supported,Medium] |
| HPA:013010_11 | 0.000991727693091 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | endometrium 1; cells in endometrial stroma[Supported,Low] |
| HPA:043010_11 | 0.00106813797148 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | skin 1; Langerhans[Supported,Low] |
| HPA:008020_11 | 0.00107375975028 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cerebral cortex; glial cells[Supported,Low] |
| HPA:028010_11 | 0.00115481824152 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | lymph node; germinal center cells[Supported,Low] |
| HPA:002020_11 | 0.00121546581402 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | appendix; lymphoid tissue[Supported,Low] |
| HPA:024010_11 | 0.00121546581402 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | kidney; cells in glomeruli[Supported,Low] |
| HPA:007030_11 | 0.00123411716067 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cerebellum; cells in molecular layer[Supported,Low] |
| HPA:016010_12 | 0.00124038171478 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | esophagus; squamous epithelial cells[Supported,Medium] |
| HPA:006020_11 | 0.00124038171478 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | caudate; neuronal cells[Supported,Low] |
| HPA:009020_11 | 0.00129136072825 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cervix, uterine; squamous epithelial cells[Supported,Low] |
| HPA:004020_12 | 0.00130434730891 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | breast; glandular cells[Supported,Medium] |
| HPA:011010_11 | 0.00131087720783 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | colon; endothelial cells[Supported,Low] |
| HPA:009010_11 | 0.00131743159386 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cervix, uterine; glandular cells[Supported,Low] |
| HPA:041010_11 | 0.0013372422865 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | skeletal muscle; myocytes[Supported,Low] |
| HPA:046010_11 | 0.00136400308101 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | smooth muscle; smooth muscle cells[Supported,Low] |
| WP:WP405 | 0.00137286558226 | 0.5 | POLR1A POLR1E | Eukaryotic Transcription Initiation |
| HPA:015010_12 | 0.00138433573475 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | epididymis; glandular cells[Supported,Medium] |
| HPA:050010_11 | 0.00139116353122 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | spleen; cells in red pulp[Supported,Low] |
| HPA:053020_12 | 0.00139116353122 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | testis; cells in seminiferous ducts[Supported,Medium] |
| HPA:055010_12 | 0.00139116353122 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | thyroid gland; glandular cells[Supported,Medium] |
| HPA:026020_11 | 0.00140489486377 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | liver; hepatocytes[Supported,Low] |
| HPA:007010_11 | 0.00145375632543 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cerebellum; Purkinje cells[Supported,Low] |
| HPA:033010_11 | 0.00146083918207 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | parathyroid gland; glandular cells[Supported,Low] |
| HPA:029010_12 | 0.00146083918207 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | nasopharynx; respiratory epithelial cells[Supported,Medium] |
| HPA:022020_11 | 0.00148224310239 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | hippocampus; neuronal cells[Supported,Low] |
| HPA:021010_11 | 0.00163100739599 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | heart muscle; myocytes[Supported,Low] |
| HPA:056010_11 | 0.00163872814106 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | tonsil; germinal center cells[Supported,Low] |
| HPA:028020_11 | 0.00166988555349 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | lymph node; non-germinal center cells[Supported,Low] |
| HPA:011020_12 | 0.00168562982594 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | colon; glandular cells[Supported,Medium] |
| HPA:057010_12 | 0.00168562982594 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | urinary bladder; urothelial cells[Supported,Medium] |
| HPA:052010_12 | 0.00168562982594 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | stomach 2; glandular cells[Supported,Medium] |
| HPA:018010_12 | 0.00169354358099 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | fallopian tube; glandular cells[Supported,Medium] |
| HPA:056030_11 | 0.00169354358099 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | tonsil; squamous epithelial cells[Supported,Low] |
| HPA:058010_11 | 0.00173353115104 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | vagina; squamous epithelial cells[Supported,Low] |
| HPA:024020_12 | 0.00174972283656 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | kidney; cells in tubules[Supported,Medium] |
| HPA:008030_11 | 0.00177422270837 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cerebral cortex; neuronal cells[Supported,Low] |
| HPA:043030_11 | 0.00179069828618 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | skin 1; keratinocytes[Supported,Low] |
| HPA:056020_11 | 0.0017989789719 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | tonsil; non-germinal center cells[Supported,Low] |
| HPA:037010_12 | 0.00180728834359 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | rectum; glandular cells[Supported,Medium] |
| HPA:030010_11 | 0.00184081401476 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | oral mucosa; squamous epithelial cells[Supported,Low] |
| HPA:014020_11 | 0.00186626272098 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | endometrium 2; glandular cells[Supported,Low] |
| HPA:012010_12 | 0.00186626272098 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | duodenum; glandular cells[Supported,Medium] |
| HPA:027010_11 | 0.00188337450156 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | lung; macrophages[Supported,Low] |
| HPA:003010_11 | 0.00188337450156 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | bone marrow; hematopoietic cells[Supported,Low] |
| GO:0006352 | 0.00188428573822 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | DNA-templated transcription, initiation |
| HPA:036010_11 | 0.00190060368677 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | prostate; glandular cells[Supported,Low] |
| HPA:039010_11 | 0.00193541641546 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | salivary gland; glandular cells[Supported,Low] |
| HPA:040010_11 | 0.00195300103416 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | seminal vesicle; glandular cells[Supported,Low] |
| HPA:013020_11 | 0.00197960229694 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | endometrium 1; glandular cells[Supported,Low] |
| HPA:029010_11 | 0.00201549224716 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | nasopharynx; respiratory epithelial cells[Supported,Low] |
| HPA:004020_11 | 0.00201549224716 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | breast; glandular cells[Supported,Low] |
| HPA:055010_11 | 0.00201549224716 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | thyroid gland; glandular cells[Supported,Low] |
| HPA:016010_11 | 0.00202454047274 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | esophagus; squamous epithelial cells[Supported,Low] |
| HPA:002010_11 | 0.00207023943365 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | appendix; glandular cells[Supported,Low] |
| HPA:032010_11 | 0.00209802753705 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | pancreas; exocrine glandular cells[Supported,Low] |
| HPA:001040_11 | 0.00212609444857 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | adrenal gland; glandular cells[Supported,Low] |
| HPA:035020_11 | 0.00216395391222 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | placenta; trophoblastic cells[Supported,Low] |
| HPA:018010_11 | 0.00217349725914 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | fallopian tube; glandular cells[Supported,Low] |
| HPA:053010_11 | 0.00217349725914 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | testis; Leydig cells[Supported,Low] |
| HPA:015010_11 | 0.00221198664973 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | epididymis; glandular cells[Supported,Low] |
| HPA:011020_11 | 0.00224118744254 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | colon; glandular cells[Supported,Low] |
| HPA:057010_11 | 0.00227067639877 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | urinary bladder; urothelial cells[Supported,Low] |
| HPA:019010_11 | 0.00227067639877 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | gallbladder; glandular cells[Supported,Low] |
| HPA:053020_11 | 0.00227067639877 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | testis; cells in seminiferous ducts[Supported,Low] |
| HPA:037010_11 | 0.00229049672659 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | rectum; glandular cells[Supported,Low] |
| HPA:051010_11 | 0.00233052636602 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | stomach 1; glandular cells[Supported,Low] |
| HPA:052010_11 | 0.00241215737618 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | stomach 2; glandular cells[Supported,Low] |
| HPA:012010_11 | 0.00242250998295 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | duodenum; glandular cells[Supported,Low] |
| HPA:045010_11 | 0.00244331513213 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | small intestine; glandular cells[Supported,Low] |
| GO:0061695 | 0.00244665292597 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | transferase complex, transferring phosphorus-containing groups |
| HPA:024020_11 | 0.00257097426756 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | kidney; cells in tubules[Supported,Low] |
| HPA:011030_10 | 0.00323406157294 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | colon; peripheral nerve/ganglion[Supported,Not detected] |
| HPA:009020_10 | 0.00524366391732 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cervix, uterine; squamous epithelial cells[Supported,Not detected] |
| HPA:009010_10 | 0.00576141778362 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cervix, uterine; glandular cells[Supported,Not detected] |
| HPA:028010_10 | 0.00584126308177 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | lymph node; germinal center cells[Supported,Not detected] |
| HPA:056030_10 | 0.0060034405125 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | tonsil; squamous epithelial cells[Supported,Not detected] |
| HPA:048010_10 | 0.00604450711606 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | soft tissue 2; adipocytes[Supported,Not detected] |
| HPA:002020_10 | 0.00604450711606 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | appendix; lymphoid tissue[Supported,Not detected] |
| HPA:033010_10 | 0.00606511924604 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | parathyroid gland; glandular cells[Supported,Not detected] |
| HPA:011010_10 | 0.00616897176327 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | colon; endothelial cells[Supported,Not detected] |
| HPA:029010_10 | 0.00621088398499 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | nasopharynx; respiratory epithelial cells[Supported,Not detected] |
| HPA:006020_10 | 0.0063379027563 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | caudate; neuronal cells[Supported,Not detected] |
| HPA:053020_10 | 0.0063379027563 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | testis; cells in seminiferous ducts[Supported,Not detected] |
| HPA:048030_10 | 0.00642365759223 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | soft tissue 2; fibroblasts[Supported,Not detected] |
| HPA:004010_10 | 0.00651027972605 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | breast; adipocytes[Supported,Not detected] |
| HPA:040010_10 | 0.00668614921926 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | seminal vesicle; glandular cells[Supported,Not detected] |
| HPA:030010_10 | 0.00673066778377 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | oral mucosa; squamous epithelial cells[Supported,Not detected] |
| HPA:056010_10 | 0.00675301024945 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | tonsil; germinal center cells[Supported,Not detected] |
| HPA:004030_10 | 0.00675301024945 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | breast; myoepithelial cells[Supported,Not detected] |
| HPA:004020_10 | 0.00677540829339 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | breast; glandular cells[Supported,Not detected] |
| HPA:026010_10 | 0.0067978620077 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | liver; bile duct cells[Supported,Not detected] |
| HPA:050020_10 | 0.0067978620077 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | spleen; cells in white pulp[Supported,Not detected] |
| HPA:003010_10 | 0.0067978620077 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | bone marrow; hematopoietic cells[Supported,Not detected] |
| HPA:043010_10 | 0.00682037148455 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | skin 1; Langerhans[Supported,Not detected] |
| HPA:043040_10 | 0.00682037148455 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | skin 1; melanocytes[Supported,Not detected] |
| HPA:043020_10 | 0.00682037148455 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | skin 1; fibroblasts[Supported,Not detected] |
| HPA:002010_10 | 0.00686555809491 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | appendix; glandular cells[Supported,Not detected] |
| HPA:043030_10 | 0.00686555809491 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | skin 1; keratinocytes[Supported,Not detected] |
| HPA:037010_10 | 0.00688823541314 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | rectum; glandular cells[Supported,Not detected] |
| HPA:011020_10 | 0.00688823541314 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | colon; glandular cells[Supported,Not detected] |
| HPA:019010_10 | 0.00691096886335 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | gallbladder; glandular cells[Supported,Not detected] |
| HPA:057010_10 | 0.00691096886335 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | urinary bladder; urothelial cells[Supported,Not detected] |
| HPA:014010_10 | 0.00691096886335 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | endometrium 2; cells in endometrial stroma[Supported,Not detected] |
| HPA:007010_10 | 0.00693375853808 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cerebellum; Purkinje cells[Supported,Not detected] |
| HPA:015010_10 | 0.00693375853808 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | epididymis; glandular cells[Supported,Not detected] |
| HPA:058010_10 | 0.00693375853808 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | vagina; squamous epithelial cells[Supported,Not detected] |
| HPA:036010_10 | 0.00695660452997 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | prostate; glandular cells[Supported,Not detected] |
| HPA:022020_10 | 0.00695660452997 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | hippocampus; neuronal cells[Supported,Not detected] |
| HPA:052010_10 | 0.00695660452997 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | stomach 2; glandular cells[Supported,Not detected] |
| HPA:022010_10 | 0.00697950693172 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | hippocampus; glial cells[Supported,Not detected] |
| HPA:014020_10 | 0.00697950693172 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | endometrium 2; glandular cells[Supported,Not detected] |
| HPA:006010_10 | 0.00697950693172 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | caudate; glial cells[Supported,Not detected] |
| HPA:024010_10 | 0.00697950693172 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | kidney; cells in glomeruli[Supported,Not detected] |
| HPA:028020_10 | 0.00697950693172 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | lymph node; non-germinal center cells[Supported,Not detected] |
| HPA:051010_10 | 0.0070024658361 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | stomach 1; glandular cells[Supported,Not detected] |
| HPA:056020_10 | 0.0070024658361 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | tonsil; non-germinal center cells[Supported,Not detected] |
| HPA:001040_10 | 0.0070024658361 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | adrenal gland; glandular cells[Supported,Not detected] |
| HPA:007020_10 | 0.0070024658361 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cerebellum; cells in granular layer[Supported,Not detected] |
| HPA:007030_10 | 0.0070024658361 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cerebellum; cells in molecular layer[Supported,Not detected] |
| HPA:016010_10 | 0.0070024658361 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | esophagus; squamous epithelial cells[Supported,Not detected] |
| HPA:013020_10 | 0.0070024658361 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | endometrium 1; glandular cells[Supported,Not detected] |
| HPA:018010_10 | 0.0070024658361 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | fallopian tube; glandular cells[Supported,Not detected] |
| HPA:027010_10 | 0.0070024658361 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | lung; macrophages[Supported,Not detected] |
| HPA:031020_10 | 0.0070024658361 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | ovary; ovarian stroma cells[Supported,Not detected] |
| HPA:012010_10 | 0.00702548133597 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | duodenum; glandular cells[Supported,Not detected] |
| HPA:008030_10 | 0.00702548133597 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cerebral cortex; neuronal cells[Supported,Not detected] |
| HPA:039010_10 | 0.00702548133597 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | salivary gland; glandular cells[Supported,Not detected] |
| HPA:053010_10 | 0.00702548133597 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | testis; Leydig cells[Supported,Not detected] |
| HPA:008050_10 | 0.00702548133597 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cerebral cortex; neuropil[Supported,Not detected] |
| HPA:008010_10 | 0.00702548133597 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cerebral cortex; endothelial cells[Supported,Not detected] |
| HPA:046010_10 | 0.00702548133597 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | smooth muscle; smooth muscle cells[Supported,Not detected] |
| HPA:026020_10 | 0.00702548133597 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | liver; hepatocytes[Supported,Not detected] |
| HPA:032010_10 | 0.00704855352427 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | pancreas; exocrine glandular cells[Supported,Not detected] |
| HPA:008020_10 | 0.00704855352427 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cerebral cortex; glial cells[Supported,Not detected] |
| HPA:021010_10 | 0.00704855352427 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | heart muscle; myocytes[Supported,Not detected] |
| HPA:027020_10 | 0.00704855352427 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | lung; pneumocytes[Supported,Not detected] |
| HPA:050010_10 | 0.00704855352427 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | spleen; cells in red pulp[Supported,Not detected] |
| HPA:045010_10 | 0.00704855352427 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | small intestine; glandular cells[Supported,Not detected] |
| HPA:035020_10 | 0.00704855352427 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | placenta; trophoblastic cells[Supported,Not detected] |
| HPA:013010_10 | 0.00704855352427 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | endometrium 1; cells in endometrial stroma[Supported,Not detected] |
| HPA:024020_10 | 0.00704855352427 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | kidney; cells in tubules[Supported,Not detected] |
| HPA:055010_10 | 0.00704855352427 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | thyroid gland; glandular cells[Supported,Not detected] |
| HPA:041010_10 | 0.00704855352427 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | skeletal muscle; myocytes[Supported,Not detected] |
| GO:0040029 | 0.00733907004762 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | regulation of gene expression, epigenetic |
| GO:0140098 | 0.00897036122651 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | catalytic activity, acting on RNA |
| HPA:014010_01 | 0.0101047263453 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | endometrium 2; cells in endometrial stroma[Uncertain,Low] |
| REAC:R-HSA-74160 | 0.0102868657133 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | Gene expression (Transcription) |
| HPA:009020_02 | 0.0113377792751 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cervix, uterine; squamous epithelial cells[Uncertain,Medium] |
| HPA:031020_01 | 0.0161885159532 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | ovary; ovarian stroma cells[Uncertain,Low] |
| HPA:006020_02 | 0.0164923137704 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | caudate; neuronal cells[Uncertain,Medium] |
| HPA:053020_13 | 0.017188862818 | 0.75 | POLR1A POLR1E ZNRD1 | testis; cells in seminiferous ducts[Supported,High] |
| HPA:013010_01 | 0.0173838936729 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | endometrium 1; cells in endometrial stroma[Uncertain,Low] |
| HPA:041010_02 | 0.017429401248 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | skeletal muscle; myocytes[Uncertain,Medium] |
| HPA:009010_02 | 0.0175664601735 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cervix, uterine; glandular cells[Uncertain,Medium] |
| HPA:058010_02 | 0.0179824901185 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | vagina; squamous epithelial cells[Uncertain,Medium] |
| HPA:050020_01 | 0.0183584591083 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | spleen; cells in white pulp[Uncertain,Low] |
| HPA:030010_02 | 0.0212634356468 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | oral mucosa; squamous epithelial cells[Uncertain,Medium] |
| HPA:007010_02 | 0.0271284914794 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cerebellum; Purkinje cells[Uncertain,Medium] |
| HPA:056030_02 | 0.0290835200664 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | tonsil; squamous epithelial cells[Uncertain,Medium] |
| HPA:014020_02 | 0.0293519558501 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | endometrium 2; glandular cells[Uncertain,Medium] |
| HPA:028010_01 | 0.0299627277978 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | lymph node; germinal center cells[Uncertain,Low] |
| HPA:002020_01 | 0.0305135939813 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | appendix; lymphoid tissue[Uncertain,Low] |
| HPA:008020_01 | 0.0322118348682 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cerebral cortex; glial cells[Uncertain,Low] |
| HPA:043010_01 | 0.0330870574545 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | skin 1; Langerhans[Uncertain,Low] |
| HPA:007030_01 | 0.0336803664422 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cerebellum; cells in molecular layer[Uncertain,Low] |
| HPA:004010_11 | 0.0342146813303 | 0.75 | POLR1A CD3EAP ZNRD1 | breast; adipocytes[Supported,Low] |
| HPA:004020_02 | 0.0358982212617 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | breast; glandular cells[Uncertain,Medium] |
| HPA:050010_01 | 0.0374095208816 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | spleen; cells in red pulp[Uncertain,Low] |
| HPA:011030_01 | 0.0378150405886 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | colon; peripheral nerve/ganglion[Uncertain,Low] |
| MIRNA:hsa-miR-6884-5p | 0.0384814873844 | 0.75 | POLR1A POLR1E CD3EAP | hsa-miR-6884-5p |
| HPA:024010_01 | 0.038968044422 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | kidney; cells in glomeruli[Uncertain,Low] |
| HPA:016010_02 | 0.0390513985277 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | esophagus; squamous epithelial cells[Uncertain,Medium] |
| HPA:011010_12 | 0.0447431662559 | 0.75 | POLR1A CD3EAP ZNRD1 | colon; endothelial cells[Supported,Medium] |
| HPA:048010_11 | 0.0458137035926 | 0.75 | POLR1A CD3EAP ZNRD1 | soft tissue 2; adipocytes[Supported,Low] |
| HPA:009020_01 | 0.0466397694984 | 1.0 | POLR1A ZNRD1 POLR1E CD3EAP | cervix, uterine; squamous epithelial cells[Uncertain,Low] |
| HPA:002020_12 | 0.0469009879466 | 0.75 | POLR1A POLR1E ZNRD1 | appendix; lymphoid tissue[Supported,Medium] |
| MIRNA:hsa-miR-485-5p | 0.0471689405073 | 0.75 | POLR1A POLR1E CD3EAP | hsa-miR-485-5p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| POLR1A | CD3EAP | 0.743 | 0.739 | hein_WMM bioplex_WMM hein (POLR1A) |
| POLR1E | POLR1A | 0.721 | 0.732 | hein_WMM bioplex_WMM hein (POLR1A) |
| POLR1E | CD3EAP | 0.352 | 0.538 | hein_WMM bioplex_WMM Malo fraction |
| POLR1A | ZNRD1 | 0.201 | 0.451 | hein_WMM hein (POLR1A) |
| CD3EAP | ZNRD1 | 0.009 | 0.101 | hein_WMM WMM_only |
| POLR1E | ZNRD1 | 0.008 | 0.06 | hein_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_04981 has an average edge precision of 0.437 which is ranked 2966 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CD3EAP | HuMAP2_00232 HuMAP2_00839 HuMAP2_02562 HuMAP2_04738 HuMAP2_04981 |
| POLR1E | HuMAP2_00232 HuMAP2_00839 HuMAP2_02562 HuMAP2_04738 HuMAP2_04981 |
| ZNRD1 | HuMAP2_00232 HuMAP2_01570 HuMAP2_02562 HuMAP2_04981 |
| POLR1A | HuMAP2_00232 HuMAP2_00839 HuMAP2_01570 HuMAP2_02439 HuMAP2_02562 HuMAP2_04738 HuMAP2_04981 |