hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04987
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MASTL | Serine/threonine-protein kinase greatwall (GW) (GWL) (hGWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L) | UniProt NCBI |
| NEFL | Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein) | UniProt NCBI |
| NEFH | Neurofilament heavy polypeptide (NF-H) (200 kDa neurofilament protein) (Neurofilament triplet H protein) | UniProt NCBI |
| C16orf70 | UPF0183 protein C16orf70 | UniProt NCBI |
| BCAS3 | Breast carcinoma-amplified sequence 3 (GAOB1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2447 | 0.00233629086428 | 0.4 | NEFL NEFH | Amyotrophic lateral sclerosis (ALS) |
| KEGG:05014 | 0.00543834659805 | 0.4 | NEFL NEFH | Amyotrophic lateral sclerosis (ALS) |
| WP:WP3680 | 0.00646864373199 | 0.4 | NEFL NEFH | Association Between Physico-Chemical Features and Toxicity Associated Pathways |
| GO:0033693 | 0.0135228859698 | 0.4 | NEFL NEFH | neurofilament bundle assembly |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| BCAS3 | C16orf70 | 0.998 | 0.94 | bioplex (C16orf70) bioplex_WMM gupta_WMM boldt_WMM |
| C16orf70 | MASTL | 0.127 | 0.4 | bioplex (C16orf70) bioplex_WMM boldt_WMM |
| NEFL | NEFH | 0.033 | 0.247 | bioplex (NEFH) bioplex_WMM |
| NEFH | C16orf70 | 0.029 | 0.231 | bioplex (C16orf70) bioplex_WMM |
| BCAS3 | MASTL | 0.008 | 0.084 | bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| NEFH | MASTL | 0.007 | 0.01 | bioplex_WMM WMM_only |
| NEFL | MASTL | 0.007 | 0.004 | bioplex_WMM boldt youn_WMM boldt_WMM |
| NEFL | BCAS3 | 0.007 | 0.006 | bioplex_WMM youn_WMM WMM_only boldt_WMM |
| NEFH | BCAS3 | 0.006 | 0.007 | bioplex_WMM WMM_only |
| NEFL | C16orf70 | 0.0 | 0.001 | bioplex (C16orf70) bioplex_WMM gupta_WMM boldt_WMM |
Images
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Complex HuMAP2_04987 has an average edge precision of 0.193 which is ranked 6272 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MASTL | HuMAP2_04880 HuMAP2_04987 HuMAP2_05294 HuMAP2_05566 |
| NEFL | HuMAP2_01819 HuMAP2_03169 HuMAP2_04023 HuMAP2_04987 |
| NEFH | HuMAP2_01819 HuMAP2_04023 HuMAP2_04987 |
| C16orf70 | HuMAP2_03057 HuMAP2_04987 HuMAP2_05294 HuMAP2_05566 |
| BCAS3 | HuMAP2_03057 HuMAP2_04987 HuMAP2_05294 HuMAP2_05566 |