hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05024
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DBNL | Drebrin-like protein (Cervical SH3P7) (Cervical mucin-associated protein) (Drebrin-F) (HPK1-interacting protein of 55 kDa) (HIP-55) (SH3 domain-containing protein 7) | UniProt NCBI |
| FGD6 | FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24) | UniProt NCBI |
| NEURL4 | Neuralized-like protein 4 | UniProt NCBI |
| ZBTB5 | Zinc finger and BTB domain-containing protein 5 | UniProt NCBI |
| HERC2 | E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6860 | 4.0241279111e-05 | 0.4 | HERC2 NEURL4 | E6AP-HERC2-MAPK6-NEURL4 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HERC2 | NEURL4 | 0.859 | 0.796 | hein_WMM bioplex_WMM hein (HERC2) gupta_WMM boldt_WMM |
| NEURL4 | DBNL | 0.588 | 0.663 | bioplex (DBNL) bioplex_WMM gupta_WMM |
| HERC2 | DBNL | 0.245 | 0.469 | bioplex (DBNL) bioplex_WMM gupta_WMM |
| FGD6 | DBNL | 0.157 | 0.416 | bioplex (DBNL) bioplex_WMM boldt boldt_WMM |
| ZBTB5 | HERC2 | 0.044 | 0.277 | hein_WMM hein (HERC2) |
| ZBTB5 | NEURL4 | 0.008 | 0.06 | hein_WMM WMM_only |
| FGD6 | NEURL4 | 0.008 | 0.042 | bioplex_WMM WMM_only |
| FGD6 | HERC2 | 0.008 | 0.019 | bioplex_WMM WMM_only |
| ZBTB5 | DBNL | 0.007 | 0.0 | youn_WMM WMM_only |
Images
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Complex HuMAP2_05024 has an average edge precision of 0.305 which is ranked 4505 out of all 6965 complexes.
Related Complexes